Advances in Delivering Protein and Peptide Therapeutics, 2nd Edition

Dear Colleagues,

Recent achievements in peptide and protein synthesis and large-scale production have revealed the high potential of these compounds as selective and efficient drugs for the treatment of a number of diseases. Currently, proteins and peptides are widely considered as prospective biopharmaceutics or vaccines and many of them are already available in clinics as oral, intravenous, subcutaneous, transdermal, and intranasal formulations. In spite of the many advantages of peptides and proteins as drugs, their wide application is limited because of some crucial obstacles. Among these, opsonization and proteolytic degradation severely affect their therapeutic efficiency. In turn, more frequent administration may cause many complications and undesirable side-effects. Moreover, the intracellular action of some peptide and protein drugs can be limited because of their poor penetration into the cell. The abovementioned problems can be overcome by different approaches, such as conjugation of peptides/proteins with polymers, encapsulation/entrapment of biopharmaceutics into polymer particles, as well as application of special systems or/and vectors for intracellular delivery.

As Guest Editors, we invite researchers to submit to this Special Issue their valuable results and findings focused on conjugation, encapsulation, entrapment, preparation of novel formulations, or other modifications to enhance stability of peptides/proteins and improve their therapeutic efficacy or intracellular delivery. Articles prepared as research papers, reviews, or short communications are welcomed for publication.

Dr. Ivan Guryanov
Dr. Evgenia G. Korzhikova-Vlakh
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.