Pediatric Gastroenteritis and Related Viral Infections
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".
Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 7267
Special Issue Editors
Interests: enteric viruses’ molecular characterization (Rotavirus, Norovirus, Astrovirus)
Interests: rotavirus; norovirus; astrovirus
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Acute gastroenteritis (AGE) is one of the most common illnesses in humans worldwide, accounting for over 200,000 pediatric deaths per year, mostly in developing countries. In developed countries, AGE is responsible for presentation to general practitioners or emergency departments and hospitalization. Several pathogens are recognized as etiologic agents of AGE in children, and four viruses are considered as clinically relevant, i.e. group A rotavirus, norovirus, adenovirus 40/41 and astrovirus. Other enteric viruses, such as toroviruses, picobirnaviruses, aichiviruses and enteroviruses, may play a minor role. Some of the major enteric viruses are characterized by high antigenic/genetic diversity and several sero/genotypes and variants have been detected, posing challenges for their classification, but also for the development of diagnostics assays and suitable vaccines. Viral AGEs may present as sporadic cases, but are commonly detected as outbreaks, particularly within close communities. Enteric viruses are easily transmitted in close settings due to low infectious dose and their environmental persistence. Their capability of spreading into the human population and causing severe clinical manifestations may be related to viral fitness and/or host susceptibility. The aim of this Special Issue is to focus on the clinical and virological features of viral AGEs, in order to acquire relevant information on: emergence and spread of common and novel viruses; effectiveness of diagnostic approaches; the possible correlations between clinical signs or severity and laboratory findings (i.e. viral load or genotypes); implementation of infection control measures and treatment. Research studies encompassing basic virology, pathogenesis, clinical virology, molecular epidemiology, measures of prevention, etc. of viral AGE are enthusiastically encouraged to be submitted to this Special Issue. Any manuscripts that are relevant to “Pediatric Gastroenteritis and Related Viral Infections” are most welcome.
Prof. Simona De Grazia
Dr. Floriana Bonura
Guest Editors
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Keywords
- viral gastroenteritis
- enteric viruses
- pathogenesis
- clinical virology
- molecular epidemiology
- vaccine
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