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Nutrients
Special Issues
Pathways Linking Nutrition with Age-Associated Cognitive and Mental Health
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Pathways Linking Nutrition with Age-Associated Cognitive and Mental Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (20 December 2023) | Viewed by 5043

Special Issue Editors

Dr. Julia Sheffler

E-Mail Website
Guest Editor
Department of Behavioral Sciences and Social Medicine, College of Medicine, Florida State University, Tallahassee, FL, USA
Interests: aging; Alzheimer’s disease; diet, interventions; health; emotion regulation; psychopathology; cognitive decline; adverse childhood experiences; lifespan
Special Issues, Collections and Topics in MDPI journals
Dr. Ravinder Nagpal

E-Mail Website
Guest Editor
Department of Nutrition and Integrative Physiology, College of Health and Human Sciences, Florida State University, Tallahassee, FL 32306, USA
Interests: nutrition and microbiome; Mediterranean diet; dietary fiber; probiotics and prebiotics; aging; nutrients for brain health
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In older adults, certain dietary patterns, nutrition, and malnutrition all play an important role in maintaining positive cognitive and emotional well-being. Prior work demonstrates that there are complex and interacting relationships between nutrition, cognitive functioning, and mental health that may be particularly impactful on the aging brain. Certain diets (e.g., MIND, DASH, ketogenic) are associated with better cognitive outcomes in older adults, as well as improved mental health and well-being.

This Special Issue aims to cover recent advances in this field, with a particular interest in elucidating pathways and mechanisms linking nutrition with cognitive and/or mental health outcomes in older adults.

We specifically are soliciting research utilizing cutting-edge analytical models, clinical trials, statistical algorithms, and experimental tools and technologies that aim to address this timely and important area of research and advance our understanding pertaining to the role of dietary and nutritional elements in cognitive and mental health in older adults.

Original research, reviews, or perspective articles providing novel insights into the pathways through which nutrition and dietary factors are associated with cognition (e.g., cognitive status, neurological health, neurodegenerative diseases) and mental health in aging adults.

Dr. Julia Sheffler
Dr. Ravinder Nagpal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • aging
  • Alzheimer's disease
  • cardiometabolic
  • cognitive health
  • dementia
  • intervention
  • longevity
  • mental health
  • memory
  • microbiome
  • neurodegenerative diseases
  • neurological health
  • nutrition
  • nutritional neuroscience
  • psychopathology
  • psychosocial

Published Papers (2 papers)

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Research

14 pages, 1151 KiB  
Article
Improving Adherence to a Mediterranean Ketogenic Nutrition Program for High-Risk Older Adults: A Pilot Randomized Trial
by Julia L. Sheffler, Dimitris N. Kiosses, Zhe He, Bahram H. Arjmandi, Neda S. Akhavan, Kamelia Klejc and Sylvie Naar
Nutrients 2023, 15(10), 2329; https://doi.org/10.3390/nu15102329 - 16 May 2023
Cited by 1 | Viewed by 2514
Abstract
(1) Background: Mediterranean ketogenic nutrition (MKN) may directly target multiple neurobiological mechanisms associated with dementia risk in older adults. Despite its promise, this type of nutrition can be challenging to learn and adhere to in a healthy manner. Our team used the National [...] Read more.
(1) Background: Mediterranean ketogenic nutrition (MKN) may directly target multiple neurobiological mechanisms associated with dementia risk in older adults. Despite its promise, this type of nutrition can be challenging to learn and adhere to in a healthy manner. Our team used the National Institutes of Health Obesity Related Behavioral Intervention Trials (NIH ORBIT) model to develop and pilot a program to help older adults with memory concerns use MKN. (2) Methods: Using a two-arm, randomized design, we evaluated an MKN Adherence (MKNA) program compared to an MKN education (MKNE) program (N = 58). The primary difference between study arms involved the use of motivational interviewing (MI) strategies and behavior change techniques (BCT) only in the MKNA arm. Participants were included if they evidenced subjective memory concerns or objective memory impairment on the Montreal Cognitive Assessment (Score 19 ≤ 26). Primary outcomes examined included feasibility, acceptability, adherence, and clinical outcomes associated with the program. (3) Results: Overall, there was relatively high program completion in both groups, with 79% of participants completing the 6-week program. The recruitment protocol required adjustment but was successful in reaching the target sample size. Retention (82%) and session attendance (91%) were higher in the MKNA arm compared to the MKNE (retention = 72%; attendance = 77%). Overall, most participants in both groups rated the program as “excellent” using the client satisfaction questionnaire. Participants in the MKNA arm evidenced higher objective and self-reported adherence to MKN during the 6-week program. Further, there was some evidence of clinical benefits of the program, although these effects diminished as adherence decreased in the 3 months follow-up. (4) Discussion: This pilot trial demonstrated that the MKN program incorporating MI and BCT strategies may better engage and retain participants than a nutrition education program alone, although participants in both groups reported high satisfaction. Full article
(This article belongs to the Special Issue Pathways Linking Nutrition with Age-Associated Cognitive and Mental Health)
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17 pages, 1077 KiB  
Article
Post-Prandial Cognitive and Blood Pressure Effects of a DHA-Rich Omega-3 Powder in Middle-Aged Males: A Pilot Study
by Andrew Pipingas, Jeffery Michael Reddan, Sarah Gauci, Lauren M. Young, Greg Kennedy, Renee Rowsell, Rebecca King, Sam Spiteri, Anne Marie Minihane and Andrew Scholey
Nutrients 2023, 15(9), 2198; https://doi.org/10.3390/nu15092198 - 5 May 2023
Viewed by 1868
Abstract
The use of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements is increasingly common among middle-aged and older adults. Users of ω-3 PUFA supplements often report using such supplements to support cognitive health, despite mixed findings reported within the ω-3 PUFA literature. To date, [...] Read more.
The use of omega-3 polyunsaturated fatty acid (ω-3 PUFA) supplements is increasingly common among middle-aged and older adults. Users of ω-3 PUFA supplements often report using such supplements to support cognitive health, despite mixed findings reported within the ω-3 PUFA literature. To date, very few studies have explored cognitive effects in distinctly middle-aged (40 to 60 years) adults, and none have examined the acute effects (in the hours following a single dose) on cognitive performance. The current study evaluated whether a single dose of ω-3 PUFA (4020 mg docosahexaenoic acid and 720 mg eicosapentaenoic acid) influences cognitive performance and cardiovascular function in middle-aged males. Cognitive performance and cardiovascular function were assessed before and 3.5–4 h after consumption of a high dose of ω-3 PUFA (DHA + EPA) or placebo, incorporated into a standardized meal (i.e., single serve of Greek yogurt). In this study of middle-aged males, no significant differential treatment effects were observed for cognitive performance. However, a significant reduction in aortic systolic blood pressure (pre-dose to post-dose) was apparent following consumption of the ω-3 PUFA (DHA + EPA) treatment (mean difference = −4.11 mmHg, p = 0.004) but not placebo (mean difference = −1.39 mmHg, p = 0.122). Future replication in a sample comprising females, as well as patients with hypertension, is merited. Full article
(This article belongs to the Special Issue Pathways Linking Nutrition with Age-Associated Cognitive and Mental Health)
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