Metabolomics by Mass Spectrometry: A Tool for Drug Development
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Pharmacology and Drug Metabolism".
Deadline for manuscript submissions: closed (22 December 2022) | Viewed by 351
Special Issue Editor
Interests: drug discovery; mass spectrometry; biomarkers; targeted therapies; anticancer drugs; drug metabolism; pharmacokinetics
Special Issue Information
Dear Colleagues,
Metabolism is often dysregulated in several diseases, including cancer or inflammatory disease.
Metabolomics is defined as a large-scale study concerning the fate and measurement of a wide range of small molecules within a biological system. Small molecule metabolites (e.g., sugars, lipids, amino acids, fatty acids) play important roles as substrates of enzymatic reactions or products; thus, metabolite changes can be studied as a function of therapeutic intervention.
The potential of mass spectrometry as an advanced analytical technique for the qualitative and quantitative measurement of numerous types of molecules has facilitated metabolomics studies and provides investigators with a unique opportunity to link therapeutic intervention with response (e.g., correlations between drug and biomarker concentration) and ultimately individualized treatment approaches. Mass spectrometry measurements are characterized by high sensitivity, selectivity, and potential for throughput.
The main aim of this Special Issue, titled “Metabolomics by Mass Spectrometry: A Tool for Drug Development” is to highlight the significance of metabolomics in the discovery of novel biomarkers and drug response enriching the available strategies for disease treatment.
Dr. Constantin Tamvakopoulos
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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