Special Issue "Synthesis of Antitumor Marine Alkaloids and Related Analogues"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: closed (30 September 2016)
Prof. Dr. Patrizia Diana
Department of Biological Chemical and Pharmaceutical Sciences and Technologies (STEBICEF), University of Palermo, Via Archirafi, 32-90123 Palermo, Italy
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Fax: +39 09123860854
Interests: marine alkaloids; heterocycles; drug discovery; synthesis; bioactive compounds; antitumor activity
Oceans have been considered as the main source of medicines and, during the past two decades, thousands of compounds and their metabolites have exhibited a wide range of biological activity. Marine organisms constitute a very important source of biologically active natural products, including some of the most potent antineoplastic agents presently discovered. Due to the small amounts of biologically active substances extracted from natural materials, several total syntheses were proposed. Moreover, due to their interesting biological activities, marine alkaloids are considered to be important lead compounds for the discovery of new biologically active compounds. The use of microbial genetics and biosynthesis are useful to develop innovative methods to discover new natural products. This Special Issue dedicated to the "Synthesis of Antitumor Marine Alkaloids and Related Analogues” hopes to emphasize the importance of the study of gene cluster identification and biosynthesis of marine organisms, the total synthesis of marine organisms, the synthesis of new marine analogues, the biological evaluation of bioactive compounds, and the studies of mode action. As the Guest Editor, I invite scientists in the fields of chemistry, biochemistry, pharmacology, and toxicology.
Prof. Patrizia Diana
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
• gene cluster
• total synthesis
• synthesis of marine analogue
• chemical transformation
• chemical modification
• antitumor activity