Special Issue "Metabolomic Approaches to Marine Organisms"

Guest Editor
Prof. Dr. Michael K. Stoskopf
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC 27607, USA
Website: http://www.cvm.ncsu.edu/docs/personnel/stoskopf_michael.html
E-Mail:
Phone: +1 919 513 6279
Fax: +1 919 513 6336
Interests: marine metabonomics; environmental pharmacokinetics; glycolipid structure; lipid profiling; marine animal health risk assessment

Guest Editor
Prof. Dr. Jeffrey Macdonald
Department of Biomedical Engineering, 5022 Burnett-Womack, University of North Carolina, Chapel Hill, NC 27599, USA
E-Mail:
Phone: +1-919-843-5154

Dear Colleagues,

Marine life has developed unique metabolic and physiologic capabilities to survive in the many varied and complex marine ecosystems. Metabolomics is the systematic study of the small-molecule metabolite profiles of organisms. These metabolites range from metabolic intermediates and hormones to other signaling molecules and secondary metabolites. Obtaining a detailed description of the metabolic pathways for marine organisms can be a key to understanding how these organisms bioprocess many of their novel compounds. This in turn can help efficiently direct the search for biochemicals with the potential to improve the health and quality of life of humans, domestic and wild animals and/or have important impacts on the environment.

This special issue dedicated to “Metabolomic Approaches to Marine Organisms” hopes to emphasize the importance of studying and understanding the metabolism of marine organisms and the role this knowledge can play in the realm of marine biodiscovery. As the Guest Editor, I invite scientists working on metabolomic questions studying marine organisms to report recent advances in the field. I look forward to working with you towards a successful special issue of the journal Marine Drugs dedicated to this under studied but important area.

Prof. Dr. Michael K. Stoskopf
Prof. Dr. Jeffrey Macdonald 
Guest Editors

Submission

All manuscripts should be submitted to marinedrugs@mdpi.com with a copy to the Guest Editor. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed Open Access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this Open Access journal is 1600 CHF per accepted paper.

• metabolomics
• metabonomics
• metabolic profiling
• xeniobiotic metabolism
• metabolic response to environmental change
• mass spectrometry
• high pressure liquid chromatography
• gas chromatography magnetic resonance imaging
• magnetic resonance spectroscopy
• comparative biochemistry
• biodiscovery

Type of Paper: Review
Title: Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems
Authors: Sophie Goulitquer *, Philippe Potin and Thierry Tonon
Affiliation: CNRS, UMR 7139 Végétaux marins et Biomolécules, Station Biologique, 29680 Roscoff, France; E-Mails: sophie.goulitquer@sb-roscoff.fr (S.G.); Potin@sb-roscoff.fr (P.P.); thierry.tonon@sb-roscoff.fr (T.T.)
Abstract: In this review, we will provide and exhaustive view of research based on LC- and GC-MS analysis in marine prokaryotes and eukaryotes. We will then describe how MS-based high-throughput metabolite profiling approaches can be used to develop systems biology approaches in marine organisms to study several biological processes, focusing on model marine macroalgae such as the brown alga Ectocarpus siliculosus. We will also illustrate the growing importance of metabolomics in chemical ecology studies in marine ecosystems, and the technical challenges related to this topic, in particular for extraction of chemical compounds from different matrices.