Mar. Drugs 2012, 10(4), 849-880; doi:10.3390/md10040849
Review

Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems

1,* email, 2,3email and 2,3email
Received: 20 February 2012; in revised form: 13 March 2012 / Accepted: 21 March 2012 / Published: 5 April 2012
(This article belongs to the Special Issue Metabolomic Approaches to Marine Organisms)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Marine systems are very diverse and recognized as being sources of a wide range of biomolecules. This review provides an overview of metabolite profiling based on mass spectrometry (MS) approaches in marine organisms and their environments, focusing on recent advances in the field. We also point out some of the technical challenges that need to be overcome in order to increase applications of metabolomics in marine systems, including extraction of chemical compounds from different matrices and data management. Metabolites being important links between genotype and phenotype, we describe added value provided by integration of data from metabolite profiling with other layers of omics, as well as their importance for the development of systems biology approaches in marine systems to study several biological processes, and to analyze interactions between organisms within communities. The growing importance of MS-based metabolomics in chemical ecology studies in marine ecosystems is also illustrated.
Keywords: metabolomics; mass spectrometry; LC-MS; GC-MS; targeted and untargeted profiling; systems biology; chemical ecology; databases
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MDPI and ACS Style

Goulitquer, S.; Potin, P.; Tonon, T. Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems. Mar. Drugs 2012, 10, 849-880.

AMA Style

Goulitquer S, Potin P, Tonon T. Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems. Marine Drugs. 2012; 10(4):849-880.

Chicago/Turabian Style

Goulitquer, Sophie; Potin, Philippe; Tonon, Thierry. 2012. "Mass Spectrometry-Based Metabolomics to Elucidate Functions in Marine Organisms and Ecosystems." Mar. Drugs 10, no. 4: 849-880.

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