Special Issue "Stem Cells and Biomaterials"

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A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).

Deadline for manuscript submissions: closed (30 April 2011)

Special Issue Editor

Guest Editor
Prof. Dr. David L. Kaplan
Departments of Biomedical Engineering & Chemical and Biological Engineering Tufts University, 4 Colby Street, Medford, MA 02155, USA
Website: http://ase.tufts.edu/faculty-guide/fac/dkaplan1.biomed.htm
E-Mail: david.kaplan@tufts.edu
Interests: extracellular matrix remodeling, biosynthesis, bioengineered spider

Special Issue Information

Dear Colleagues,

The innate ability of stem cells to self-renew and differentiate into multiple cell types makes them a promising source for tissue regeneration applications.  This capacity to self-renew and differentiate is heavily influenced by the microenvironment. Therefore, to consistently and efficiently control the fate determination of stem cells, it is necessary to replicate the physical, chemical, and biological signals found in the microenvironment, both spatially and temporally.  Engineered biomaterials have the potential to mimic and control the physical, chemical and biologic factors necessary for guided stem cell differentiation.  They are currently being investigated to act as scaffolds to guide and improve 3D tissue formation, substrates to enhance cell culturing techniques, vehicles for cell delivery, and sources of immobilized and/or time released factors.  These biomaterials are being applied to the regeneration of numerous tissue types, including bone, cartilage, fat, myocardium and nerves, among others, and are being used to enhance the engraftment of modified adult stem cells.  The continued advancement of biomaterials holds the promise of improved therapies for numerous conditions.

Prof. Dr. David L. Kaplan
Guest Editor

Keywords

  • mesenchymal stem cell
  • hematopoietic stem cell
  • induced pluripotent stem cell
  • embryonic stem cell
  • hydrogel
  • electrospun fibers
  • tissue engineering
  • 3D scaffolds
  • tissue regeneration
  • silk
  • stem cell niche

Published Papers (6 papers)

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Displaying article 1-6
p. 155-172
by , , ,  and
J. Funct. Biomater. 2011, 2(3), 155-172; doi:10.3390/jfb2030155
Received: 15 July 2011; Accepted: 4 August 2011 / Published: 8 August 2011
Show/Hide Abstract | Cited by 2 | PDF Full-text (487 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
p. 119-154
by ,  and
J. Funct. Biomater. 2011, 2(3), 119-154; doi:10.3390/jfb2030119
Received: 26 May 2011; in revised form: 29 June 2011 / Accepted: 12 July 2011 / Published: 4 August 2011
Show/Hide Abstract | Cited by 14 | PDF Full-text (677 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
p. 107-118
by , , , , , , ,  and
J. Funct. Biomater. 2011, 2(3), 107-118; doi:10.3390/jfb2030107
Received: 21 June 2011; Accepted: 18 July 2011 / Published: 20 July 2011
Show/Hide Abstract | Cited by 3 | PDF Full-text (1011 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
abstract graphic
p. 88-106
by , , ,  and
J. Funct. Biomater. 2011, 2(3), 88-106; doi:10.3390/jfb2030088
Received: 24 May 2011; in revised form: 11 June 2011 / Accepted: 21 June 2011 / Published: 24 June 2011
Show/Hide Abstract | Cited by 9 | PDF Full-text (739 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
p. 39-66
by , , , , , , , , ,  and
J. Funct. Biomater. 2011, 2(2), 39-66; doi:10.3390/jfb2020039
Received: 4 May 2011; in revised form: 25 May 2011 / Accepted: 17 June 2011 / Published: 21 June 2011
Show/Hide Abstract | Cited by 6 | PDF Full-text (1337 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
p. 67-87
by , , , ,  and
J. Funct. Biomater. 2011, 2(2), 67-87; doi:10.3390/jfb2020067
Received: 6 May 2011; in revised form: 7 June 2011 / Accepted: 17 June 2011 / Published: 21 June 2011
Show/Hide Abstract | Cited by 5 | PDF Full-text (530 KB) | HTML Full-text | XML Full-text
(This article belongs to the Special Issue Stem Cells and Biomaterials)
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Last update: 26 February 2014

J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert