Special Issue "Stem Cells and Biomaterials"
A special issue of Journal of Functional Biomaterials (ISSN 2079-4983).
Deadline for manuscript submissions: closed (30 April 2011)
Prof. Dr. David L. Kaplan
Departments of Biomedical Engineering & Chemical and Biological Engineering Tufts University, 4 Colby Street, Medford, MA 02155, USA
Interests: extracellular matrix remodeling, biosynthesis, bioengineered spider
The innate ability of stem cells to self-renew and differentiate into multiple cell types makes them a promising source for tissue regeneration applications. This capacity to self-renew and differentiate is heavily influenced by the microenvironment. Therefore, to consistently and efficiently control the fate determination of stem cells, it is necessary to replicate the physical, chemical, and biological signals found in the microenvironment, both spatially and temporally. Engineered biomaterials have the potential to mimic and control the physical, chemical and biologic factors necessary for guided stem cell differentiation. They are currently being investigated to act as scaffolds to guide and improve 3D tissue formation, substrates to enhance cell culturing techniques, vehicles for cell delivery, and sources of immobilized and/or time released factors. These biomaterials are being applied to the regeneration of numerous tissue types, including bone, cartilage, fat, myocardium and nerves, among others, and are being used to enhance the engraftment of modified adult stem cells. The continued advancement of biomaterials holds the promise of improved therapies for numerous conditions.
Prof. Dr. David L. Kaplan
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- mesenchymal stem cell
- hematopoietic stem cell
- induced pluripotent stem cell
- embryonic stem cell
- electrospun fibers
- tissue engineering
- 3D scaffolds
- tissue regeneration
- stem cell niche
Article: Multi-Composite Bioactive Osteogenic Sponges Featuring Mesenchymal Stem Cells, Platelet-Rich Plasma, Nanoporous Silicon Enclosures, and Peptide Amphiphiles for Rapid Bone Regeneration
J. Funct. Biomater. 2011, 2(2), 39-66; doi:10.3390/jfb2020039
Received: 4 May 2011; in revised form: 25 May 2011 / Accepted: 17 June 2011 / Published: 21 June 2011| Download PDF Full-text (1337 KB) | Download XML Full-text
J. Funct. Biomater. 2011, 2(2), 67-87; doi:10.3390/jfb2020067
Received: 6 May 2011; in revised form: 7 June 2011 / Accepted: 17 June 2011 / Published: 21 June 2011| Download PDF Full-text (530 KB) | Download XML Full-text
J. Funct. Biomater. 2011, 2(3), 88-106; doi:10.3390/jfb2030088
Received: 24 May 2011; in revised form: 11 June 2011 / Accepted: 21 June 2011 / Published: 24 June 2011| Download PDF Full-text (739 KB) | Download XML Full-text
Article: A Novel Pulsatile Bioreactor for Mechanical Stimulation of Tissue Engineered Cardiac Constructs
J. Funct. Biomater. 2011, 2(3), 107-118; doi:10.3390/jfb2030107
Received: 21 June 2011 / Accepted: 18 July 2011 / Published: 20 July 2011| Download PDF Full-text (1011 KB) | Download XML Full-text
J. Funct. Biomater. 2011, 2(3), 119-154; doi:10.3390/jfb2030119
Received: 26 May 2011; in revised form: 29 June 2011 / Accepted: 12 July 2011 / Published: 4 August 2011| Download PDF Full-text (677 KB) | Download XML Full-text
J. Funct. Biomater. 2011, 2(3), 155-172; doi:10.3390/jfb2030155
Received: 15 July 2011 / Accepted: 4 August 2011 / Published: 8 August 2011| Download PDF Full-text (487 KB) | Download XML Full-text
Last update: 4 October 2012