Targeted Treatment in Head–Neck Cancer

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Otolaryngology".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 365

Special Issue Editors


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Guest Editor
Division of Otolaryngology and Head and Neck Surgery, European Institute of Oncology IRCCS, 20142 Milan, Italy
Interests: endoscopes; skull base; cancer; head and neck surgery; otolaryngology; larynx

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Guest Editor
Department of Otolaryngology Head and Neck Surgery, Regina Elena National Cancer Institute IRCCS, 00144 Rome, Italy
Interests: head and neck cancer; robotic surgery; oropharyngeal cancer; laryngeal cancer; rare neoplasm in head and neck

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Guest Editor
Otolaryngology Department, Isola Tiberina-Gemelli Isola Hospital, 00186 Rome, Italy
Interests: head and neck oncology; major salivary glands surgery, laryngeal cancer; thyroid cancer; molecular biomarkers
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Special Issue Information

Dear Colleagues,

This Special Issue to explore the advancements and challenges in personalized and precision medicine approaches for the management of head and neck cancer. This Special Issue invites original research articles that delve into various aspects of targeted treatment for head–neck cancer. We encourage submissions focusing on novel targeted therapies, immunotherapy and other precision medicine approaches that address the unique characteristics of head and neck tumors.

We seek comprehensive research articles, clinical studies, experimental investigations and translational studies that shed light on the latest developments in targeted treatment within the field of head–neck cancer. However, please note that this Special Issue will not consider mini-reviews or case reports.

We look forward to receiving your submissions and contributing to the collective understanding of targeted treatment potential in improving outcomes for patients with head and neck cancer.

Dr. Jacopo Zocchi
Dr. Gerardo Petruzzi
Dr. Pietro De Luca
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • head and neck squamous cell carcinoma
  • precision medicine
  • targeted therapies
  • immunotherapy
  • tumor heterogeneity
  • treatment response monitoring

Published Papers (1 paper)

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Review

19 pages, 318 KiB  
Review
Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours
by Jodie L. M. Tham, Sweet Ping Ng, Richard Khor, Morikatsu Wada, Hui Gan, Alesha A. Thai, June Corry, Houda Bahig, Antti A. Mäkitie, Sandra Nuyts, Remco De Bree, Primož Strojan, Wai Tong Ng, Avraham Eisbruch, James C. H. Chow and Alfio Ferlito
J. Clin. Med. 2024, 13(11), 3020; https://doi.org/10.3390/jcm13113020 - 21 May 2024
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Abstract
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques [...] Read more.
The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs. Full article
(This article belongs to the Special Issue Targeted Treatment in Head–Neck Cancer)
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