Neonatal Neurology: New Insights, Diagnosis and Treatment

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Pediatrics".

Deadline for manuscript submissions: 15 September 2024 | Viewed by 1507

Special Issue Editor


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Guest Editor
Child Neurology and Neurorehabilitation Unit, Department of Pediatrics, Regional Hospital of Bolzano, 39100 Bolzano, Italy
Interests: neonatal seizures; neonatal neurology; neonatal diagnostics

Special Issue Information

Dear Colleagues,

Neonatal neurology is a rapidly advancing field.

There is an increasing request for neonatal brain monitoring and for earlier diagnoses, in order to provide information regarding prognosis and guidelines for treatment and interventions.

On one side, there is an increasing interest in developing standardized trainings for clinicians and reliable tools for neurological examination of newborns. On the other side, instrumental tools for brain monitoring and brain imaging are developing quickly, with increasing interest in automated analyses (authomated tools for EEG/aEEG analyses) and in possible further tools (i.e. NIRS) to be applied for neurocritical care in the neonatal intensive care units.

In the present Special Issue, we would like to provide an overview on the current advances in the field, both by means of reviews, case reports and case series on new or educational diagnoses, and current studies on EEG/aEEG and other tools appliable in the NICUs for diagnoses and monitoring of the neurologic conditions and brain health of both term and preterm newborns.

Dr. Elena Pavlidis
Guest Editor

Manuscript Submission Information

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Keywords

  • brain imaging
  • neonatal neurology
  • newborns
  • neurologic conditions
  • pediatric brain health

Published Papers (1 paper)

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18 pages, 381 KiB  
Systematic Review
Cranial MRI beyond the Neonatal Period and Neurodevelopmental Outcomes in Neonatal Encephalopathy Due to Perinatal Asphyxia: A Systematic Review
by Corline E. J. Parmentier, Tobias Kropman, Floris Groenendaal, Maarten H. Lequin, Linda S. de Vries, Manon J. N. L. Benders and Thomas Alderliesten
J. Clin. Med. 2023, 12(24), 7526; https://doi.org/10.3390/jcm12247526 - 6 Dec 2023
Viewed by 944
Abstract
Background: Magnetic resonance imaging (MRI) including diffusion-weighted imaging within seven days after birth is widely used to obtain prognostic information in neonatal encephalopathy (NE) following perinatal asphyxia. Later MRI could be useful for infants without a neonatal MRI or in the case of [...] Read more.
Background: Magnetic resonance imaging (MRI) including diffusion-weighted imaging within seven days after birth is widely used to obtain prognostic information in neonatal encephalopathy (NE) following perinatal asphyxia. Later MRI could be useful for infants without a neonatal MRI or in the case of clinical concerns during follow-up. Therefore, this review evaluates the association between cranial MRI beyond the neonatal period and neurodevelopmental outcomes following NE. Methods: A systematic literature search was performed using PubMed and Embase on cranial MRI between 2 and 24 months after birth and neurodevelopmental outcomes following NE due to perinatal asphyxia. Two independent researchers performed the study selection and risk of bias analysis. Results were separately described for MRI before and after 18 months. Results: Twelve studies were included (high-quality n = 2, moderate-quality n = 6, low-quality n = 4). All reported on MRI at 2–18 months: seven studies demonstrated a significant association between the pattern and/or severity of injury and overall neurodevelopmental outcomes and three showed a significant association with motor outcome. There were insufficient data on non-motor outcomes and the association between MRI at 18–24 months and neurodevelopmental outcomes. Conclusions: Cranial MRI performed between 2 and 18 months after birth is associated with neurodevelopmental outcomes in NE following perinatal asphyxia. However, more data on the association with non-motor outcomes are needed. Full article
(This article belongs to the Special Issue Neonatal Neurology: New Insights, Diagnosis and Treatment)
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