Special Issue "Advances in Proteomic Research 2014"
Deadline for manuscript submissions: closed (10 April 2014)
Prof. Dr. David Sheehan (Website)
Proteomic Research Laboratory, Head of School of Biochemistry and Cell Biology, University College Cork, Western Gateway Building, Western Rd, Cork, Ireland
Phone: 353 21 4904207
Fax: +35 321 427 4034
Interests: enzymology and evolution of glutathione transferases; application of proteomics to study of oxidative stress; implications of reactive oxygen and nitrogen species for kidney function; environmental toxicology; nanomaterials as emerging toxicological threats
Proteins are the main agents of biological change. Their structural diversity is sufficient to accomplish the enormous array of chemical functionality required by living cells. Unlike the genome, the proteome (the complement of proteins under a given set of biological conditions) is a dynamic quantity which varies with variables such as cell cycle stage, cell specialization, pathology and nutritional status. Thus proteomics offers a robust set of high-throughput methods to explore changes in the quantity and status of specific proteins so as to reveal changes underlying key facets of biological functioning. Importantly, this is a discovery-driven, rather than a hypothesis-driven, approach with the potential to identify new processes not suspected a priori. This Special Issue will contain articles describing new advances in the science of proteomics.
Topics of this Special Issue include, but are not limited to:
- Sample preparation for two dimensional electrophoresis
- Sample preparation for protein mass spectrometry
- Enrichment for sub-proteomes
- Organelle proteomics
- Clinical applications of proteomics, such as biomarker discovery
- Environmental proteomics
- Proteomics in food science
- Proteomics of non-model organisms
- Proteomics databases
- New Bioinformatics approaches for proteomics datasets
- Use of protein arrays
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed Open Access monthly journal published by MDPI.
- two dimensional electrophoresis
- protein arrays
- protein mass spectrometry