Therapeutic Polymers for Drug Delivery
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: closed (31 August 2022) | Viewed by 29911
Special Issue Editors
Interests: development of new drug delivery systems; therapeutic polymers for drug delivery; methods of micro- and nanoencapsulation of drugs; medical devices; food supplements; cosmetics; drug dissolution; absorption; metabolism and elimination studies; targeted therapies; in vivo efficacy and safety assessments using animal models; preclinical toxicity assessment; regulatory affairs
Special Issues, Collections and Topics in MDPI journals
Interests: drug delivery systems; lipid-based systems; establishment of murine models and alternative routes of administration; pharmacokinetic and biodistribution studies; infectious diseases; melanoma; colon cancer; inflammation; in vitro and in vivo studies
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Polymeric materials have been applied for decades in therapeutic applications such as drug delivery and tissue regeneration, mainly due to their biocompatibility and suitable mechanical properties. Polymeric therapeutics encompass, at the same time, drug–polymer conjugates, polymer–protein conjugates and supramolecular drug-delivery systems based on well-defined multivalent and dendritic polymers. In case of polymer–drug conjugates, they have been used as bioactive pharmaceuticals owing to their increased drug efficacy, solubility, and target specificity. On the other hand, several polymer–protein conjugates made by anchoring enzymes or biologically relevant proteins to polyethylene glycol components have demonstrated a significant improvement in stability and pharmacokinetic properties.
An overview of polymeric therapeutics in drug delivery will be herein presented, with a focus on key concepts, polymerization methods, new approaches that have been applied to improve the control of polymer structure and examples that characterize the relevant features of these novel drug-delivery systems. This Special Issue will cover a variety of polymer-based therapeutics in greater detail, including noncovalent and covalent polymeric delivery vehicles (nanoparticles, liposomes, dendrimers), polymer sequestrants, and polymerized drugs, and the recent advances in this emerging area.
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Prof. Catarina Pinto ReisDr. Maria Manuela Gaspar
Guest Editors
Manuscript Submission Information
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Keywords
- Drug-polymer conjugates
- Polymer-protein conjugates
- Supramolecular drug-delivery system
- Polymer chemistry
- Molecular biology
- Proteins
- Enzymes
- In vitro and in vivo studies
- Efficacy and safety assessment