Research on Intracellular Signal Transduction Systems

Dear Colleagues,

A variety of extracellular stimuli induce specific cell responses, such as proliferation, differentiation, survival, and death, in virtually all types of cells. Receptors, when occupied by their extracellular ligands, transduce signals into the cell by diverse mechanisms, including the production of second messengers, protein–protein interactions, and post-translational modifications of signaling proteins, leading to gene expression, cytoskeletal rearrangements, and so on. Some of the signaling pathways and their components are common in many types of cells, while others are unique to specific cell types. In addition, aberrations in the intracellular signaling systems of human cells are intimately associated with the development and progression of diseases such as cancer, cardiovascular disease, neurodegenerative disease, and diabetes.

This Special Issue, “Research on Intracellular Signal Transduction Systems”, aims to provide new insights into the physiological functions and regulatory mechanisms of any type of intracellular signal transduction system, ranging from microorganisms to higher organisms. Authors are invited to submit original research and review articles related to these subjects.

Prof. Dr. Takaya Satoh
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• signal transduction
• receptor
• G protein
• kinase
• second messenger
• gene expression
• cytoskeleton
• human disease