Molecular Pharmacology and Metabolism of Phytochemicals
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: 15 May 2024 | Viewed by 1536
Special Issue Editor
Interests: phytochemicals; chemoprevention; antioxidant defences; anti-inflammation; hair growth; phase II enzymes; signal transduction
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Natural compounds are increasingly featured in medical treatments. Exogenous natural compounds are more likely to be used in this context, either alone or more commonly as supplements to traditional therapies. Phytochemicals, bioactive chemical compounds found in plants, have long been studied for their potential health benefits. Many phytochemicals have been shown to induce cellular defense mechanisms against exposure to various endogenous and exogenous toxicants as well as reactive oxygen and nitrogen species (ROS/RNS). Inhibition of pro-inflammatory and carcinogenic molecular targets is also a cellular defense strategy of phytochemicals to prevent chronic diseases and maintain health. Improving the gut microbiome profile with phytochemicals could be another recent approach to enhancing defense ability.
However, the pharmacology and metabolism of phytochemicals and other natural compounds are less studied and characterized, even though phytochemicals have been present in human biological systems for thousands of years. In this context, the pharmacology and metabolism of phytochemicals and other natural compounds are critical. Without addressing it, it could lead to unforeseen toxicity or treatment failure. On the contrary, with well-defined pharmacokinetics, pharmacodynamics, and metabolism (or biotransformation), natural compounds like phytochemicals can be applied more widely in medical and health conditions and used more properly to achieve better therapeutic outcomes, which will benefit patients.
This Special Issue calls for original research articles and reviews that address the progress and current understanding in the overlapping research topics of “Molecular Pharmacology and Metabolism of Phytochemicals”.
Prof. Dr. Woo-Sik Jeong
Guest Editor
Manuscript Submission Information
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Keywords
- phytochemicals
- natural compounds
- metabolism
- antioxidant
- anti-inflammation
- pharmacokinetics
- pharmacodynamics