Special Issue "Long Noncoding RNAs"
Deadline for manuscript submissions: closed (31 May 2015)
Prof. Dr. Bernhard Herrmann
Director, Max-Planck-Institute for Molecular Genetics (MPI-MG), Department Developmental Genetics, Ihnestr. 63-73, D-14195 Berlin, Germany
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Interests: developmental genetics of the mouse; trunk development; regulatory networks controlling tissue formation and organ development; EMT; epigenetic control mechanisms; long noncoding RNA; tumorigenesis; non-Mendelian inheritance in the mouse
Improved sequencing technology has revealed a large number of genes expressing non protein-coding RNA with unknown function. One subclass, the long noncoding RNAs have recently come into focus since many have been found to be associated with histone modifying complexes involved in gene regulation and cell lineage control. So far only a small number of lncRNAs have been shown to play an important role in cell differentiation, organogenesis or cancer. However, current data suggest that lncRNAs play pivotal roles in many cellular processes besides gene regulation and nuclear organization, and may be involved in many diseases.
This special issue of Genes welcomes reviews and original papers covering recent research on the function of long noncoding RNA in embryogenesis, cell differentiation, homeostasis and disease processes. Contributions on all aspects of long noncoding RNA function are welcome.
Prof. Dr. Bernhard Herrmann
Manuscript Submission Information
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- long noncoding rna
- cell differentiation
- tissue homeostasis
- histone modifying complexes
- nuclear structure organization
- gene regulation
- rna/protein complexes