Special Issue "Loop Entropy"
A special issue of Entropy (ISSN 1099-4300).
Deadline for manuscript submissions: closed (20 December 2012)
Prof. Dr. Gregory S. Chirikjian
Department of Mechanical Engineering, Johns Hopkins University, 223 Latrobe Hall, 3400 North Charles Street, Baltimore, MD 21218-2682, USA
Interests: computational structural biology (in particular, computational mechanics of large proteins); conformational statistics of biological macromolecules; developed theory for "hyper-redundant" (snakelike) robot motion planning; designs and builds hyper-redundant robotic manipulator arms; applied mathematics (applications of group theory in engineering); self-replicating robotic systems
Macromolecules such as polypeptides and nucleic acids form the basis for all living things. These molecules typically fold into tertiary structures that have highly ordered regions. However, it is often the case that some aspects of these tertiary structures remain underdetermined when viewed as a static object. This underdetermination manifests itself in the form of hinge and breathing motions, allosteric reorganization, intrinsically disordered regions, and loop motions. In this special issue of Entropy, models of the various aspects of conformational variability in biological macromolecules are examined. Concepts from polymer theory, statistical thermodynamics, computer science, molecular dynamics simulation, stochastic modeling, and information theory will be used to model the conformational disorder of biomolecules both in their denatured and folded states.
Gregory S. Chirikjian
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Entropy is an international peer-reviewed Open Access monthly journal published by MDPI.
- statistical mechanics
- molecular simulation
- stochastic models
- Brownian motion
- protein folding
- polymer theory
Entropy 2011, 13(11), 1958-1966; doi:10.3390/e13111958
Received: 1 October 2011; in revised form: 10 November 2011 / Accepted: 18 November 2011 / Published: 24 November 2011| Download PDF Full-text (119 KB)
Entropy 2012, 14(2), 213-232; doi:10.3390/e14020213
Received: 1 January 2012; in revised form: 27 January 2012 / Accepted: 3 February 2012 / Published: 10 February 2012| Download PDF Full-text (878 KB)
Entropy 2012, 14(2), 252-290; doi:10.3390/e14020252
Received: 26 December 2011; in revised form: 10 January 2012 / Accepted: 3 February 2012 / Published: 13 February 2012| Download PDF Full-text (3695 KB)
Entropy 2012, 14(3), 581-598; doi:10.3390/e14030581
Received: 30 January 2012; in revised form: 13 March 2012 / Accepted: 16 March 2012 / Published: 22 March 2012| Download PDF Full-text (1541 KB)
Entropy 2012, 14(4), 687-700; doi:10.3390/e14040687
Received: 16 February 2012; in revised form: 27 March 2012 / Accepted: 29 March 2012 / Published: 10 April 2012| Download PDF Full-text (493 KB) | Supplementary Files
Entropy 2013, 15(3), 1085-1099; doi:10.3390/e15031085
Received: 11 January 2013; in revised form: 18 February 2013 / Accepted: 12 March 2013 / Published: 18 March 2013| Download PDF Full-text (2378 KB) | Supplementary Files
Last update: 11 June 2012