Molecular Nutrition: How Nutrients and Nutraceuticals Could Impact on Aging and Longevity

Dear Colleagues,

Aging is a worldwide phenomenon and the increase of the median age is evident everywhere. Oldest old people are the population with the fastest growth in Western World but the healthy lifespan is not going at the same pace. The role of nutrition and lifestyle in the modulation of aging rate and in the improvement of the lifespan has been validated by a huge amount of evidence but the specific effects at a molecular level are often unknown. It is useful to start from the basis to build new knowledge: the molecular pattern is essential to really use specific molecules and, consequently personalized medicine, in order to “treat” a specific phenotype, as the aged ones. As it is well known, each daily action can contribute to increase or decrease the rate of aging. Thus, molecular modifications linked to specific nutrients (e.g., phytochemicals) and the interaction with other aspects such as life habit, physical activities, meditation and any other action that can modify molecular aspects and pathways, could be interesting to identify new crucial aspects contributing to the increase or decrease of successful (longevity) or unsuccessful aging. This Special Issue wants to collect reviews about current knowledge on the interaction of specific nutrient or nutrient components on aging and longevity at a molecular level. Looking at the molecular aspects and biochemical pathways, we would collect new evidence or review about the possible modulation of these two phenotypes to try to find new hallmarks and molecular biomarkers.

Dr. Giulia Accardi
Dr. Anna Aiello
Guest Editors

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• nutrition
• nutraceutical
• aging
• longevity
• molecular nutrition
• signalling pathway