Special Issue "Catalyzed Synthesis of Natural Products"

A special issue of Catalysts (ISSN 2073-4344).

Deadline for manuscript submissions: 30 April 2018

Special Issue Editor

Guest Editor
Prof. David Díez

Universidad de Salamanca, Department of Organic Chemistry, Salamanca, Castilla y León, Spain
Website | E-Mail
Phone: 0034923294500
Interests: Synthesis; Organic Synthesis; Synthetic Organic Chemistry; Medicinal and Pharmaceutical Chemistry

Special Issue Information

Dear Colleagues,

Natural products play pivotal roles not only in drug discovery, but in the transformation and synthesis of new material. The Organic Synthesis have been always next to natural products not only to corroborate their structure but too to obtain many derivatives in order to increase their activity and reduce secondary effects. In the last years, there has been a removed interest in doing the synthesis of natural products in a catalytic manner.This special issue collects original research papers, reviews and commentaries focused on the challenges for catalyzed synthesis of natural products. Submissions are welcome especially (but not exclusively) in the following areas:

Organocatalyzed synthesis of natural products;

Catalyzed synthesis of Natural Products with metals: this part could be divided into catalyzed by noble metals or first row metals;

Biocatalytic Synthesis of Natural Products: this part could be divided into using enzymes or using microorganisms.

Prof. David Díez
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Catalysts is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • synthesis
  • catalysis
  • natural products
  • organocatalysis
  • biocatalysis
  • noble metals
  • first row metals
  • enzymes
  • microorganisms

Published Papers (1 paper)

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Open AccessArticle Biotransformation of Ergostane Triterpenoid Antcin K from Antrodia cinnamomea by Soil-Isolated Psychrobacillus sp. AK 1817
Catalysts 2017, 7(10), 299; doi:10.3390/catal7100299
Received: 22 September 2017 / Revised: 2 October 2017 / Accepted: 3 October 2017 / Published: 11 October 2017
PDF Full-text (1681 KB) | HTML Full-text | XML Full-text | Supplementary Files
Antcin K is one of the major ergostane triterpenoids from the fruiting bodies of Antrodia cinnamomea, a parasitic fungus that grows only on the inner heartwood wall of the aromatic tree Cinnamomum kanehirai Hay (Lauraceae). To search for strains that have the
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Antcin K is one of the major ergostane triterpenoids from the fruiting bodies of Antrodia cinnamomea, a parasitic fungus that grows only on the inner heartwood wall of the aromatic tree Cinnamomum kanehirai Hay (Lauraceae). To search for strains that have the ability to biotransform antcin K, a total of 4311 strains of soil bacteria were isolated, and their abilities to catalyze antcin K were determined by ultra-performance liquid chromatography analysis. One positive strain, AK 1817, was selected for functional studies. The strain was identified as Psychrobacillus sp., based on the DNA sequences of the 16S rRNA gene. The biotransformation metabolites were purified with the preparative high-performance liquid chromatography method and identified as antcamphin E and antcamphin F, respectively, based on the mass and nuclear magnetic resonance spectral data. The present study is the first to report the biotransformation of triterpenoids from A. cinnamomea (Antrodia cinnamomea). Full article
(This article belongs to the Special Issue Catalyzed Synthesis of Natural Products)

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