Oxidative Stress and Cancer: Possible Beneficial and Antioxidant Strategies (Volume II)

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue, “Oxidative Stress and Cancer: Possible Beneficial and Antioxidant Strategies” (https://www.mdpi.com/journal/cancers/special_issues/Melatonin_cancer).

The incidence of cancer, a leading cause of death, is constantly increasing.

As we develop a better understanding of the molecular complexity underlying carcinogenesis, interventions can be established for specific mechanisms.

Despite this complexity, scientific breakthroughs have led to the discovery of the various ways in which a cell can undergo tumor transformation. Eukaryotic cells mainly depend on the consumption of oxygen, and many of their activities are related to a balance among reactive oxygen intermediates and nitrogen species. The increase in oxidative stress, if not adequately compensated for by an antioxidant defense, has a significant impact on the quality of life, inducing many inflammatory processes linked to DNA mutation and tumor development.

Proper therapeutic intervention requires a good knowledge of carcinogenesis. Melatonin has demonstrated its role in the modulation of carcinogenesis, but its mechanisms remain obscure.

This Special Issue will highlight oxidative stress and cancer, covering both basic and more (pre)clinical aspects needed to improve therapies.

Prof. Dr. Rita Rezzani
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• oxidative
• stress
• antioxidant
• melatonin
• carcinogenesis