Algorithms and Data Analysis of High Throughput Sequencing in Cancers

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Informatics and Big Data".

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 275

Special Issue Editors


E-Mail Website
Guest Editor
1. Institute of Oncology Research, Faculty of Biomedical Sciences, Università della Svizzera Italiana, 6500 Bellinzona, Switzerland
2. Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland
Interests: bioinformatics; biostatistics; non-coding RNAs; lymphoma; high-throughput sequencing data analysis; diagnostic and prognostic biomarkers discovery
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Laboratory of Molecular Biology, Mario Negri Institute for Pharmacological Research, 20156 Milano, Italy
Interests: gene expression; human genetics; genomics; computational biology; next-generation sequencing; bioinformatics and computational biology; cancer genomics

Special Issue Information

Dear Colleagues,

The acquisition of cancer hallmarks requires molecular alterations at multiple levels, including genome, epigenome, transcriptome, proteome, and metabolome levels. High-throughput DNA sequencing has contributed to the identification of cancer-specific mutations, epigenetic alterations, and molecular subtyping of tumors.  Moreover, large-scale tumor molecular profiling programs across different cancer types hold the promise of improving diagnostics, prognostics, and personalized treatment.

High-throughput omics data create huge bioinformatic challenges including storage, transmission, manipulation, and analysis, making the downstream processing of data a daunting task.

Therefore, new bioinformatic methods are required to biologically extract sequencing data from meaningful information and present them in an easily interpretable format.

In this Special Issue, we will discuss bioinformatic methodologies and statistical approaches, with a special emphasis on how the omics data are being analyzed, stored, and manipulated to aspire or create new ways of diagnosing and treating cancers.

Dr. Luciano Cascione
Dr. Marco Bolis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • computational biology
  • bioinformatics
  • machine learning
  • artificial intelligence
  • next-generation sequencing
  • oncology
  • cancer
  • precision medicine

Published Papers

There is no accepted submissions to this special issue at this moment.
Back to TopTop