Mass Spectrometry-Based “Omics” Approaches in Cancer Research

Dear Colleagues,

Over the past two decades, the words "omics" has expanded from the initial "genomics" to a wide range of biomolecular disciplines directed toward the study of RNA species (transcriptomics), proteins (proteomics), lipids (lipidomics), glycans (glycomics), and metabolites (metabolomics). The spread of omics disciplines has been possible mainly through the development of novel and high-throughput mass spectrometry technologies and informatics tools capable of generating large amounts of data related to different levels of biological complexity (DNA, mRNA, proteins, metabolites, etc.).

Emerging omics technologies are likely to influence the development of omics-based analysis of cancer in the future, as both the types and numbers of molecular measurements continue to increase. Furthermore, the combination of different omics approaches generates more comprehensive information, ultimately leading to a deeper understanding of cancer. There is a strong interest to push “omics” technologies in the direction of highly personalized medicine to achieve targeted therapies capable of halting tumor progression.

The purpose of this Special Issue is to deliver recent advances of mass spectrometry‐based “omics” application in cancer helping in biomarker discovery for early diagnosis, prognosis, and appropriate therapeutics.

Dr. Rita Casadonte
Dr. Kristina Schwamborn
Guest Editors

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• biomarker discovery
• cancer
• mass spectrometry
• “omics”