Special Issue "Addiction and Neuroadaptation"

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A special issue of Brain Sciences (ISSN 2076-3425).

Deadline for manuscript submissions: closed (30 June 2012)

Special Issue Editor

Guest Editor
Dr. Marcelo Febo
Assistant Professor of Psychiatry & Program Director of Translational Research Imaging, University of Florida McKnight Brain Institute, 1149 S. Newell Dr., Suite L4-100F, Gainesville, FL 32611, USA
Website: http://psychiatry.ufl.edu/Faculty-And-Staff/Directories/Faculty/Febo-Marcelo/
E-Mail: febo@ufl.edu
Phone: +1 352 294 4911
Interests: functional magnetic resonance imaging of awake animals; neuropeoptide modulation of maternal care in rats

Special Issue Information

Dear Colleagues,

One of the defining features of drug addiction is the high rate of relapse to drug seeking and taking even after prolonged abstinence periods. Regressing towards drug intake in spite of the negative consequences, and the inability to control intake, strongly suggests that the brain undergoes enduring and perhaps permanent neurobiological changes that need to be fully understood before effective treatments are established. Advancements in our knowledge of the biological underpinnings of addictive disorders have greatly increased over the past decade. Animal studies modeling distinct phases such as sustained drug intake, withdrawal, extinction and relapse are instrumental to gaining insight on neurobiological mechanisms. This has been accompanied by conceptual shifts in our understanding of the control of gene expression, discoveries of the synaptic and molecular events involved in long-term plasticity and memory, and developments of translational neuroimaging tools that provide a global view of brain activity and brain structural changes. This special issue will bring together original research and review articles on the neural correlates of addiction, primarily focused on ‘neuroadaptive mechanisms’ and how these brain changes may impact behavior even after protracted abstinence. More studies using specialized techniques to probe in vivo brain activity, unique animal models to correlate neural substrates and behavior, and articles introducing novel concepts and discoveries are needed to further expand the breadth of our current knowledge of this disease impacting society on a global scale.

Dr. Marcelo Febo
Guest Editor

Keywords

  • addiction
  • drug
  • reward
  • drug abuse
  • animal models
  • neuroimaging
  • reinforcer
  • conditioning
  • memory
  • plasticity
  • gene expression
  • molecular
  • neuroadaptations

Published Papers (15 papers)

by  and
Brain Sci. 2013, 3(2), 504-520; doi:10.3390/brainsci3020504
Received: 23 January 2013; in revised form: 4 March 2013 / Accepted: 20 March 2013 / Published: 10 April 2013
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by
Brain Sci. 2013, 3(1), 159-176; doi:10.3390/brainsci3010159
Received: 22 December 2012; in revised form: 9 January 2013 / Accepted: 25 January 2013 / Published: 15 February 2013
Show/Hide Abstract | Cited by 1 | PDF Full-text (406 KB) | HTML Full-text | XML Full-text

by ,  and
Brain Sci. 2013, 3(1), 143-158; doi:10.3390/brainsci3010143
Received: 25 October 2012; in revised form: 11 December 2012 / Accepted: 24 January 2013 / Published: 4 February 2013
Show/Hide Abstract | Cited by 3 | PDF Full-text (1407 KB) | HTML Full-text | XML Full-text

by , ,  and
Brain Sci. 2012, 2(4), 667-683; doi:10.3390/brainsci2040667
Received: 20 September 2012; in revised form: 13 November 2012 / Accepted: 23 November 2012 / Published: 27 November 2012
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by , , ,  and
Brain Sci. 2012, 2(4), 619-633; doi:10.3390/brainsci2040619
Received: 20 September 2012; in revised form: 26 October 2012 / Accepted: 8 November 2012 / Published: 13 November 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (283 KB) | HTML Full-text | XML Full-text

by , , ,  and
Brain Sci. 2012, 2(4), 605-618; doi:10.3390/brainsci2040605
Received: 1 August 2012; in revised form: 26 September 2012 / Accepted: 8 November 2012 / Published: 12 November 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (214 KB) | HTML Full-text | XML Full-text

by  and
Brain Sci. 2012, 2(4), 573-588; doi:10.3390/brainsci2040573
Received: 4 October 2012; in revised form: 19 October 2012 / Accepted: 24 October 2012 / Published: 31 October 2012
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by , , ,  and
Brain Sci. 2012, 2(4), 553-572; doi:10.3390/brainsci2040553
Received: 31 July 2012; in revised form: 10 September 2012 / Accepted: 24 October 2012 / Published: 30 October 2012
Show/Hide Abstract | Cited by 5 | PDF Full-text (442 KB) | HTML Full-text | XML Full-text

by ,  and
Brain Sci. 2012, 2(4), 523-552; doi:10.3390/brainsci2040523
Received: 12 July 2012; in revised form: 5 September 2012 / Accepted: 25 September 2012 / Published: 17 October 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (383 KB) | HTML Full-text | XML Full-text

by ,  and
Brain Sci. 2012, 2(4), 434-482; doi:10.3390/brainsci2040434
Received: 31 July 2012; in revised form: 11 September 2012 / Accepted: 11 September 2012 / Published: 1 October 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (320 KB) | HTML Full-text | XML Full-text

by ,  and
Brain Sci. 2012, 2(3), 421-433; doi:10.3390/brainsci2030421
Received: 31 July 2012; in revised form: 4 September 2012 / Accepted: 11 September 2012 / Published: 20 September 2012
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by , , , ,  and
Brain Sci. 2012, 2(3), 375-404; doi:10.3390/brainsci2030375
Received: 3 July 2012; in revised form: 24 August 2012 / Accepted: 28 August 2012 / Published: 12 September 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (1412 KB) | HTML Full-text | XML Full-text

by  and
Brain Sci. 2012, 2(3), 347-374; doi:10.3390/brainsci2030347
Received: 28 June 2012; in revised form: 24 August 2012 / Accepted: 28 August 2012 / Published: 5 September 2012
Show/Hide Abstract | Cited by 16 | PDF Full-text (242 KB) | HTML Full-text | XML Full-text

by , , , , ,  and
Brain Sci. 2012, 2(3), 298-318; doi:10.3390/brainsci2030298
Received: 9 May 2012; in revised form: 6 July 2012 / Accepted: 10 August 2012 / Published: 20 August 2012
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by , , ,  and
Brain Sci. 2012, 2(2), 242-253; doi:10.3390/brainsci2020242
Received: 10 April 2012; in revised form: 4 May 2012 / Accepted: 1 June 2012 / Published: 11 June 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (389 KB) | HTML Full-text | XML Full-text

Last update: 25 February 2014

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