Special Issue "Protein SUMOylation"

Quicklinks

A special issue of Biomolecules (ISSN 2218-273X).

Deadline for manuscript submissions: closed (28 February 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Seth Blackshaw
Associate Professor, Department of Neuroscience, Johns Hopkins University, School of Medicine, BRB 332 733 N. Broadway Avenue, Baltimore, MD 21287, USA
Website: http://neuroscience.jhu.edu/SethBlackshaw.php
E-Mail: sblack@jhmi.edu
Phone: (443) 287-5609
Fax: (410) 502-1872
Interests: transcriptional control of neural and glial development; protein SUMOylation; noncoding RNAs; functional proteomics; chronobiology

Special Issue Information

Dear Colleagues,

SUMOylation has emerged as a reversible and widely used means of modulating the activity and localization of many different classes of protein. Originally thought to primarily regulate nuclear processes such as transcription and DNA repair, recent work has revealed that SUMOylation plays a critical role in such diverse functions as regulating kinase and G-protein activity, cytoskeletal structure and ion channel function. It is now appreciated that site-specific SUMOylation guides cellular differentiation, regulates neuronal activity, and is misregulated in a range of human diseases. This issue intends to both review recent findings and to showcase original research in this fast moving field.

We thus invite submission of research and review manuscripts that cover any aspect of the biochemistry, cell biology, genetics or pharmacology of SUMO, SUMOylation enzymes and their cellular substrates and effector molecules. Areas of particular interest include, but are not limited to, advances in SUMOylation-dependent regulation of transcription factor activity and chromatin structure, dynamic regulation of SUMOylation by intracellular signaling, novel functional classes of proteins regulated by SUMOylation, and the role of SUMOylation in embryonic development, cancer and neurodegeneration. Other potential topics include the biology of the growing number of E3 SUMO ligases, SUMO binding proteins, and new genetic and pharmacological techniques for modulating protein SUMOylation in vivo.

We look forward to reading your contributions,

Prof. Dr. Seth Blackshaw
Guest Editor

Keywords

  • SUMO and SUMOylation
  • cytoskeleton
  • neurodegeneration
  • development and differentiation
  • ion channel and synapse
  • proteomics cell dynamics
  • Transcription and gene expression
  • protein transport stability and structure
  • ubiquitin, acetylation,  phosphorylation, and post-translational modification
  • protease
  • chromatin and epigenetics
  • signal transduction

Published Papers (8 papers)

by , , ,  and
Biomolecules 2012, 2(3), 312-330; doi:10.3390/biom2030312
Received: 16 June 2012; in revised form: 5 July 2012 / Accepted: 13 July 2012 / Published: 25 July 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (1223 KB) | HTML Full-text | XML Full-text
abstract graphic

by ,  and
Biomolecules 2012, 2(3), 331-349; doi:10.3390/biom2030331
Received: 13 June 2012; in revised form: 23 June 2012 / Accepted: 25 June 2012 / Published: 25 July 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (575 KB) | HTML Full-text | XML Full-text
abstract graphic

by ,  and
Biomolecules 2012, 2(3), 350-375; doi:10.3390/biom2030350
Received: 10 June 2012; in revised form: 27 June 2012 / Accepted: 13 July 2012 / Published: 25 July 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (1095 KB) | HTML Full-text | XML Full-text
abstract graphic

by , ,  and
Biomolecules 2012, 2(2), 269-281; doi:10.3390/biom2020269
Received: 3 May 2012; in revised form: 14 May 2012 / Accepted: 16 May 2012 / Published: 24 May 2012
Show/Hide Abstract | PDF Full-text (475 KB) | HTML Full-text | XML Full-text
abstract graphic

by ,  and
Biomolecules 2012, 2(2), 256-268; doi:10.3390/biom2020256
Received: 14 April 2012; in revised form: 24 April 2012 / Accepted: 24 April 2012 / Published: 14 May 2012
Show/Hide Abstract | Cited by 1 | PDF Full-text (646 KB) | HTML Full-text | XML Full-text
abstract graphic

by  and
Biomolecules 2012, 2(2), 240-255; doi:10.3390/biom2020240
Received: 15 March 2012; in revised form: 28 March 2012 / Accepted: 9 April 2012 / Published: 23 April 2012
Show/Hide Abstract | PDF Full-text (291 KB) | HTML Full-text | XML Full-text
abstract graphic

by
Biomolecules 2012, 2(2), 203-227; doi:10.3390/biom2020203
Received: 21 February 2012; in revised form: 21 March 2012 / Accepted: 27 March 2012 / Published: 5 April 2012
Show/Hide Abstract | Cited by 2 | PDF Full-text (680 KB) | HTML Full-text | XML Full-text
abstract graphic

by , , , , , , ,  and
Biomolecules 2012, 2(1), 34-45; doi:10.3390/biom2010034
Received: 30 November 2011; in revised form: 5 January 2012 / Accepted: 20 January 2012 / Published: 30 January 2012
Show/Hide Abstract | Cited by 6 | PDF Full-text (336 KB) | HTML Full-text | XML Full-text
abstract graphic

Last update: 25 February 2014

Biomolecules EISSN 2218-273X Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert