Special Issue "Protein SUMOylation"
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: closed (28 February 2012)
Prof. Dr. Seth Blackshaw
The Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, 329 Broadway Research Building, 725 North Wolfe St., Baltimore, MD 21205, USA
Phone: +1 443 287 5609
Fax: +1 410 614 9568
Interests: transcriptional control of neural and glial development; protein SUMOylation; noncoding RNAs; functional proteomics; chronobiology
SUMOylation has emerged as a reversible and widely used means of modulating the activity and localization of many different classes of protein. Originally thought to primarily regulate nuclear processes such as transcription and DNA repair, recent work has revealed that SUMOylation plays a critical role in such diverse functions as regulating kinase and G-protein activity, cytoskeletal structure and ion channel function. It is now appreciated that site-specific SUMOylation guides cellular differentiation, regulates neuronal activity, and is misregulated in a range of human diseases. This issue intends to both review recent findings and to showcase original research in this fast moving field.
We thus invite submission of research and review manuscripts that cover any aspect of the biochemistry, cell biology, genetics or pharmacology of SUMO, SUMOylation enzymes and their cellular substrates and effector molecules. Areas of particular interest include, but are not limited to, advances in SUMOylation-dependent regulation of transcription factor activity and chromatin structure, dynamic regulation of SUMOylation by intracellular signaling, novel functional classes of proteins regulated by SUMOylation, and the role of SUMOylation in embryonic development, cancer and neurodegeneration. Other potential topics include the biology of the growing number of E3 SUMO ligases, SUMO binding proteins, and new genetic and pharmacological techniques for modulating protein SUMOylation in vivo.
We look forward to reading your contributions,
Prof. Dr. Seth Blackshaw
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 300 CHF (Swiss Francs). English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- SUMO and SUMOylation
- development and differentiation
- ion channel and synapse
- proteomics cell dynamics
- Transcription and gene expression
- protein transport stability and structure
- ubiquitin, acetylation, phosphorylation, and post-translational modification
- chromatin and epigenetics
- signal transduction
Biomolecules 2012, 2(1), 34-45; doi:10.3390/biom2010034
Received: 30 November 2011; in revised form: 5 January 2012 / Accepted: 20 January 2012 / Published: 30 January 2012| Download PDF Full-text (336 KB) | Download XML Full-text
Biomolecules 2012, 2(2), 203-227; doi:10.3390/biom2020203
Received: 21 February 2012; in revised form: 21 March 2012 / Accepted: 27 March 2012 / Published: 5 April 2012| Download PDF Full-text (680 KB) | Download XML Full-text
Biomolecules 2012, 2(2), 240-255; doi:10.3390/biom2020240
Received: 15 March 2012; in revised form: 28 March 2012 / Accepted: 9 April 2012 / Published: 23 April 2012| Download PDF Full-text (291 KB) | Download XML Full-text
Biomolecules 2012, 2(2), 256-268; doi:10.3390/biom2020256
Received: 14 April 2012; in revised form: 24 April 2012 / Accepted: 24 April 2012 / Published: 14 May 2012| Download PDF Full-text (646 KB) | Download XML Full-text
Biomolecules 2012, 2(2), 269-281; doi:10.3390/biom2020269
Received: 3 May 2012; in revised form: 14 May 2012 / Accepted: 16 May 2012 / Published: 24 May 2012| Download PDF Full-text (475 KB) | Download XML Full-text
Article: SUMOylation in Giardia lamblia: A Conserved Post-Translational Modification in One of the Earliest Divergent Eukaryotes
Biomolecules 2012, 2(3), 312-330; doi:10.3390/biom2030312
Received: 16 June 2012; in revised form: 5 July 2012 / Accepted: 13 July 2012 / Published: 25 July 2012| Download PDF Full-text (1223 KB) | Download XML Full-text
Biomolecules 2012, 2(3), 331-349; doi:10.3390/biom2030331
Received: 13 June 2012; in revised form: 23 June 2012 / Accepted: 25 June 2012 / Published: 25 July 2012| Download PDF Full-text (575 KB) | Download XML Full-text
Review: SUMO Wrestles with Recombination
Biomolecules 2012, 2(3), 350-375; doi:10.3390/biom2030350
Received: 10 June 2012; in revised form: 27 June 2012 / Accepted: 13 July 2012 / Published: 25 July 2012| Download PDF Full-text (1095 KB) | Download XML Full-text
Last update: 25 September 2012