Special Issue "Next Generation Sequencing Approaches in Biology"

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A special issue of Biology (ISSN 2079-7737).

Deadline for manuscript submissions: closed (31 July 2012)

Special Issue Editor

Guest Editor
Prof. Dr. Mario Stanke
University of Greifswald, Institute for Mathematics and Computer Science, 17487 Greifswald, Germany
Website: http://www.math-inf.uni-greifswald.de/mathe/index.php/mitarbeiter/382-prof-dr-mario-stanke
E-Mail: mario.stanke@uni-greifswald.de

Special Issue Information

Dear Colleagues,

New fast and cheap DNA sequencing technologies from an increasing number of different platforms have forwarded biological research applications such as the sequencing of new genomes, the resequencing of individuals' genomes and the analysis of gene expression. While only in the last decade a single genome sequencing project used to keep a large consortium busy for years, now many sequencing projects target dozens, hundreds or even thousands of genomes in a single undertaking. The new technology also promises to make medicine more individual and enhance the understanding of the genotype's influence on diseases and traits. However, next generation sequencing technologies also bring new challenges, such as the requirement of more efficient mapping and assembly algorithms, the necessity to deal with shorter reads or with reads that have a higher error rate. Other challenges in distributed computing arise from the much larger data sizes. This special issue will cover original research papers on bioinformatical and statistical methods that make use of next generation sequencing. The submission of reviews is also welcomed.

Prof. Dr. Mario Stanke
Guest Editor

Keywords

  • RNA-seq
  • assembly
  • expression analysis
  • mapping
  • alignment
  • gene finding
  • SNPs
  • genome-wide association
  • copy number variations
  • cloud computing
  • ChIP-seq

Published Papers (12 papers)

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Displaying article 1-12
p. 378-398
by ,  and
Biology 2013, 2(1), 378-398; doi:10.3390/biology2010378
Received: 21 January 2013; in revised form: 21 January 2013 / Accepted: 4 February 2013 / Published: 1 March 2013
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 895-905
by , ,  and
Biology 2012, 1(3), 895-905; doi:10.3390/biology1030895
Received: 28 August 2012; in revised form: 21 September 2012 / Accepted: 7 December 2012 / Published: 14 December 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 766-777
by , , , , , , ,  and
Biology 2012, 1(3), 766-777; doi:10.3390/biology1030766
Received: 5 October 2012; in revised form: 14 November 2012 / Accepted: 20 November 2012 / Published: 5 December 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 658-667
by
Biology 2012, 1(3), 658-667; doi:10.3390/biology1030658
Received: 24 October 2012; in revised form: 24 October 2012 / Accepted: 7 November 2012 / Published: 16 November 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 575-596
by , , ,  and
Biology 2012, 1(3), 575-596; doi:10.3390/biology1030575
Received: 30 August 2012; in revised form: 9 October 2012 / Accepted: 12 October 2012 / Published: 25 October 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 495-507
by , , , ,  and
Biology 2012, 1(3), 495-507; doi:10.3390/biology1030495
Received: 1 August 2012; in revised form: 31 August 2012 / Accepted: 25 September 2012 / Published: 1 October 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
abstract graphic
p. 460-483
by ,  and
Biology 2012, 1(3), 460-483; doi:10.3390/biology1030460
Received: 6 August 2012; in revised form: 7 August 2012 / Accepted: 13 September 2012 / Published: 25 September 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 439-459
by , , , ,  and
Biology 2012, 1(2), 439-459; doi:10.3390/biology1020439
Received: 16 July 2012; in revised form: 5 September 2012 / Accepted: 6 September 2012 / Published: 18 September 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 395-410
by ,  and
Biology 2012, 1(2), 395-410; doi:10.3390/biology1020395
Received: 27 July 2012; in revised form: 22 August 2012 / Accepted: 31 August 2012 / Published: 12 September 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 383-394
by  and
Biology 2012, 1(2), 383-394; doi:10.3390/biology1020383
Received: 25 July 2012; in revised form: 14 August 2012 / Accepted: 20 August 2012 / Published: 31 August 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 370-382
by , , , , , , , , ,  and
Biology 2012, 1(2), 370-382; doi:10.3390/biology1020370
Received: 12 July 2012; in revised form: 9 August 2012 / Accepted: 10 August 2012 / Published: 27 August 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
p. 297-310
by  and
Biology 2012, 1(2), 297-310; doi:10.3390/biology1020297
Received: 24 July 2012; in revised form: 3 August 2012 / Accepted: 9 August 2012 / Published: 15 August 2012
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(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
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Last update: 25 February 2014

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