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Biology 2012, 1(3), 658-667; doi:10.3390/biology1030658
Review

Methods, Challenges and Potentials of Single Cell RNA-seq

Received: 24 October 2012; in revised form: 24 October 2012 / Accepted: 7 November 2012 / Published: 16 November 2012
(This article belongs to the Special Issue Next Generation Sequencing Approaches in Biology)
View Full-Text   |   Download PDF [221 KB, uploaded 16 November 2012]
Abstract: RNA-sequencing (RNA-seq) has become the tool of choice for transcriptomics. Several recent studies demonstrate its successful adaption to single cell analysis. This allows new biological insights into cell differentiation, cell-to-cell variation and gene regulation, and how these aspects depend on each other. Here, I review the current single cell RNA-seq (scRNA-seq) efforts and discuss experimental protocols, challenges and potentials.
Keywords: RNA-seq; scRNA-seq; single cell RNA-seq; scRNA-seq; single cell
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Hebenstreit, D. Methods, Challenges and Potentials of Single Cell RNA-seq. Biology 2012, 1, 658-667.

AMA Style

Hebenstreit D. Methods, Challenges and Potentials of Single Cell RNA-seq. Biology. 2012; 1(3):658-667.

Chicago/Turabian Style

Hebenstreit, Daniel. 2012. "Methods, Challenges and Potentials of Single Cell RNA-seq." Biology 1, no. 3: 658-667.


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