Dear Colleagues,

After two to three decades where various hypotheses and strategies were proposed and tested, most of which failed when facing industrial scale-up or real clinical usefulness, applications of technological approaches and platforms using nano-scaled systems (nanomedicine) are progressively assuming value in medicine as well as in clinical practice. We are now in a time where nanotechnology is mature enough to efficiently address its potentiality towards patients’ care, which is called “translational nanomedicine”. In this regard, proposals of new biomaterials and production methods from researchers are increasingly tailored to industrial feasibility and, above all, clinical needs. For many years, cancer therapy has been gaining interest in drug delivery research, and today, other fields have become more and more attractive for nanotechnological tools, such as protein and peptide delivery, antimicrobial delivery, vaccine delivery, gene therapy, rare diseases, and, even more recently, medical device industry.

This Special Issue is aimed at collecting relevant and high-level experimental studies on the new biomaterials and matrices that are able to produce nanosystems and nanodevices for the controlled release and targeting of drugs and other bioactive compounds. Moreover, particular attention will be devoted to “green nanomedicine”, as well as to bio-inspired, bioengineered, and biomimetic drug delivery carriers (such as virosomes, biohybrid drug delivery systems, bioengineered bacterial outer membrane vesicles, etc.). Finally, research incorporating preclinical or clinical results will certainly be of great interest.  

Assoc. Prof. Dr. Pio Maria Furneri
Dr. Virginia Fuochi
Prof. Rosario Pignatello
Guest Editors

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• drug targeting
• antibacterial drugs
• gene delivery
• antiviral drugs
• anticancer agents
• nanomedicine
• biomimetic drug delivery carriers
• green nanomedicine
• bioengineered bacterial outer membrane vesicles
• virosomes