Special Issue "Ultrasound in Extraction Processing"

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Acoustics and Vibrations".

Deadline for manuscript submissions: 30 November 2018

Special Issue Editors

Guest Editor
Prof. Dr. Farid Chemat

Green Extraction Team, Université d'Avignon et des Pays de Vaucluse, INRA, Avignon Cedex 84029, France
Website | E-Mail
Phone: 0033490144465
Interests: green extraction; alternative solvents; innovative technologies; microwave; ultrasound
Guest Editor
Prof. Dr. Muthupandian Ashokkumar

School of Chemistry, Faculty of Science, University of Melbourne, VIC 3010, Australia
Website | E-Mail
Interests: sonochemistry; ultrasonics

Special Issue Information

Dear Colleagues,

Ultrasound-assisted extraction is a “hot” research topic which affects several fields of modern plant-based chemistry. Ultrasound is a key-technology in achieving the objective of the “sustainable” and “green” extraction of natural products. Using ultrasound, full extractions can now be completed in minutes with high reproducibility, reducing the consumption of solvent, simplifying manipulation and work-up, giving higher purity of the final product, eliminating post-treatment of waste water, and consuming only a fraction of the fossil energy normally needed for conventional extraction methods. This special issue will present a complete picture of the current knowledge on ultrasound-assisted extraction (UAE) in food ingredients and products, nutraceutics, cosmetic, pharmaceutical, and bioenergy applications. The present Special Issue, “Ultrasound in Extraction Processing”, aims to collect and publish recent advances in this interdisciplinary area in the form of reviews and research articles dealing with extraction by ultrasound, the techniques and their combinations, the mechanisms, applications from laboratory to industry, security, and environmental impacts. Experts are welcome to give their opinion about how Ultrasound Extraction contributed/contributes/will contribute to the natural products area, possible trends, and perspectives.

Prof. Dr. Farid Chemat

Prof. Dr. Muthupandian Ashokkumar


Guest Editor

Manuscript Submission Information

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Keywords

  • Green extraction, separation, and purification

  • Intensification

  • Mechanisms

  • Combination with green and biobased solvents

  • Combination with innovative and hybrid techniques

Published Papers (3 papers)

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Research

Open AccessArticle Enhanced Harnessing of the Graviola Bioactive Components Using a Neoteric Sonication Cum Microwave Coadjuvant Extraction Protocol
Appl. Sci. 2018, 8(2), 232; https://doi.org/10.3390/app8020232
Received: 23 November 2017 / Revised: 25 January 2018 / Accepted: 29 January 2018 / Published: 2 February 2018
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Abstract
Graviola is one of the most accomplished natural anticancer therapists gaining popularity in recent times. Harnessing the full benefit from tapping all of its rich bioactive reservoirs is absolutely worthy and mandatory. It is in this regard that a well optimized extraction methodology
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Graviola is one of the most accomplished natural anticancer therapists gaining popularity in recent times. Harnessing the full benefit from tapping all of its rich bioactive reservoirs is absolutely worthy and mandatory. It is in this regard that a well optimized extraction methodology gains paramount importance. In case of Graviola, no sophistication in terms of extraction methods is reported. A neoteric sonication cum microwave combined extraction technology was introduced that maximized the extraction process and minimized (7 min) the extraction time. The extraction efficiency was validated based on the significant enrichment of bioactive ingredients in Graviola extracts following the sonication cum microwave combined protocol. Full article
(This article belongs to the Special Issue Ultrasound in Extraction Processing)
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Graphical abstract

Open AccessArticle Enhancement of Chlorophyll a Production from Marine Spirulina maxima by an Optimized Ultrasonic Extraction Process
Appl. Sci. 2018, 8(1), 26; https://doi.org/10.3390/app8010026
Received: 2 November 2017 / Revised: 13 December 2017 / Accepted: 20 December 2017 / Published: 25 December 2017
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Abstract
Under the optimal ultrasonification extraction conditions of 20.52 kHz for the frequency, 32.59 °C for the temperature, and 4.91 h for the process time, 17.98 mg/g of chlorophyll a was obtained. It was much higher than 13.81 mg/g from conventional 70% ethanol extraction
[...] Read more.
Under the optimal ultrasonification extraction conditions of 20.52 kHz for the frequency, 32.59 °C for the temperature, and 4.91 h for the process time, 17.98 mg/g of chlorophyll a was obtained. It was much higher than 13.81 mg/g from conventional 70% ethanol extraction and even higher than other data from Spirulina. This yield was close to the predicted value of 18.21 mg/g from the second-order polynomial model with a regression coefficient of 0.969. This model showed the greatest significance with the ultrasonic frequency and process time and the least significance with the temperature. The extracts also showed high α,α-diphenyl-β-picrylhydrazyl (DPPH) radical scavenging activities as 69.38%, compared to 58.25% for the extracts from the 70% ethanol extraction. It was first shown that the optimal extraction was effective at enhancing the neuroprotective activities possibly due to the synergistic effects of higher amounts of chlorophyll a and other bioactive substances in the extract, revealing a 90% protection of the growth of mouse neuronal cells and a great reduction in Reactive Oxygen Species (ROS) production. Full article
(This article belongs to the Special Issue Ultrasound in Extraction Processing)
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Open AccessArticle Enhancement of Skin Anti-Inflammatory Activities of Eclipta prostrata L. from the Ultrasonic Extraction Process
Appl. Sci. 2017, 7(12), 1227; https://doi.org/10.3390/app7121227
Received: 17 November 2017 / Accepted: 21 November 2017 / Published: 28 November 2017
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Abstract
This work first showed that the skin anti-inflammatory activities of Eclipta prostrata L. (E. prostrata L.)n be increased through an ultrasonic extraction process at a frequency of 120 kHz with 70% ethanol at 40 °C for 6 h. The extract from the
[...] Read more.
This work first showed that the skin anti-inflammatory activities of Eclipta prostrata L. (E. prostrata L.)n be increased through an ultrasonic extraction process at a frequency of 120 kHz with 70% ethanol at 40 °C for 6 h. The extract from the ultrasound extraction (UE) contained 378.6 mg/100 g of wedelolactone (a major bioactive substance in E. prostrata L.), compared with the 172.9 mg/100 g from a conventional extraction process with 70% ethanol at 80 °C for 12 h (EE). The UE showed less than 10% of low cytotoxicity against normal fibroblast cells, and also exhibited much higher antioxidant activities than that from the EE when treating with 0.3 mg/mL of the extracts. It was proved that the high antioxidant activities of the UE were closely correlated with the enhancement of skin anti-inflammatory activities by effectively suppressing the production of tumor necrosis factor-alpha and interleukin-6 from macrophages. The production of prostaglandin E2 from human skin cells was also greatly reduced, compared with the EE for all ranges of the treatments. These results strongly indicate that the various biological activities of E. prostrata L. can be improved by a simple ultrasound extraction process because of the high elution of bioactive substances even at a low temperature. Full article
(This article belongs to the Special Issue Ultrasound in Extraction Processing)
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