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Bioactive Compounds from Food: Structure, Biological Activity and Health Effects

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (20 July 2021) | Viewed by 2948

Special Issue Editors


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Guest Editor
Department of Surgical, Oncological and Oral Sciences (DICHIRONS), University of Palermo, 90127 Palermo, Italy
Interests: nutrition; endocrinology; food science thyroid hormones; vitamins; micronutrients; antioxidant activity of foods
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Special Issue Information

Dear Colleagues,

We are pleased to announce a Special Issue of Applied Sciences entitled “Bioactive Compounds from Food: Structure, Biological Activity and Health Effects”. The new frontiers in food science are aimed at identifying specific interactions between different components of functional foods and their capability to modulate genomic, cellular, biochemical, or physiologic functions that can be potentially beneficial for human health. Polyphenols, flavonoids, vitamins, pigments, trace elements, phytoestrogens, and many other substances are known to be essential components of most foods that may help prevent disease and maintain vital body functions. The main goal of this Special Issue of Applied Sciences is to provide the most recent insights into the biochemical mechanisms through which functional molecules in food can modulate the redox balance of human cells and tissues in order to maintain internal homeostasis and structural integrity and to prevent the onset of chronic degenerative diseases.

The Guest Editors would like to invite potential contributors to submit their manuscripts on these topics including original research, systematic reviews, mini-reviews, and prospective articles.

Prof. Dr. Marco Giammanco
Prof. Dr. Herbert Ryan Marini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • food
  • nutrition
  • nutraceutical
  • oxidative stress
  • inflammation
  • polyphenols
  • flavonoids
  • vitamin
  • micronutrients
  • phytoestrogens
  • hormones

Published Papers (1 paper)

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Research

13 pages, 1565 KiB  
Article
Inhibition of Urease, Elastase, and β-Glucuronidase Enzymatic Activity by Applying Aqueous Extracts of Opuntia oligacantha C.F. Först Acid Fruits: In Vitro Essay under Simulated Digestive Conditions
by Gabriela Medina-Pérez, Laura Peralta-Adauto, Laura Afanador-Barajas, Fabián Fernández-Luqueño, Elizabeth Pérez-Soto, Rafael Campos-Montiel and Armando Peláez-Acero
Appl. Sci. 2021, 11(16), 7705; https://doi.org/10.3390/app11167705 - 21 Aug 2021
Cited by 3 | Viewed by 2345
Abstract
Non-communicable diseases such as gastric inflammatory diseases and the hepatic pathologies are mainly related to bad lifestyle habits such as recurrent consumption of non-steroidal anti-inflammatory drugs (NSAIDs), excessive intake of alcohol, tobacco, steroids (high doses), alkaline agents, strong acid foods, and high-fat food, [...] Read more.
Non-communicable diseases such as gastric inflammatory diseases and the hepatic pathologies are mainly related to bad lifestyle habits such as recurrent consumption of non-steroidal anti-inflammatory drugs (NSAIDs), excessive intake of alcohol, tobacco, steroids (high doses), alkaline agents, strong acid foods, and high-fat food, and Helicobacter pylori infections, among others. The fruit of Opuntia oligacantha C.F. Först var. Ulapa (xoconostle) is currently being studied due its nutritional and functional properties. The objective of the present study was to evaluate gastroprotective, anti-inflammatory, and hepatoprotective activities of different parts of xoconostle fruit by establishing in vitro simulated gastrointestinal conditions. Four treatments were established to test aqueous extracts (pericarp (P), mesocarp (M), endocarp (E) and whole fruit (W)). The quantified bioactive compounds were the total phenols, flavonoids, tannins, and betalains. The enzymatic assays were: urease, elastase, and β-glucuronidase. Significant differences (p < 0.05) of bioactive compounds content were measured in xoconostle extracts, the highest concentration was found in W (phenols 313 mg GAE/100 g, flavonoids 189 mg QE/100 g, tannins 71 mg CATE/100 g). The betalains content was higher in E; 17 mg/100 g significant differences were observed (p < 0.05) in the enzymatic inhibitions test (urease, elastase and β-glucuronidase), where W presented the highest inhibition activity (86%, 79%, and 84%), respectively. Bioactive compounds after in vitro gastrointestinal tests were maintained above 60% enzymatic inhibition activity. Full article
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