Special Issue "Monoclonal Antibody Preparation against Natural Product and Its Application"
A special issue of Antibodies (ISSN 2073-4468).
Deadline for manuscript submissions: closed (31 August 2012)
Prof. Dr. Yukihiro Shoyama
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan
Phone: (+81) 956-20-5653
Fax: (+81) 956-20-5622
Interests: monoclonal antibodies; bioactive compounds; marihuana study; isolation and structure elucidation; biotechnology
As the rapid development of the molecular biosciences and their biotechnological application, immunoassay system using monoclonal antibody (MAb) against drugs and bioactive natural products having small molecular weight have become important tools for studies on quantitative and/or qualitative analytical techniques, enzyme assay and receptor binding analysis owing to their specific affinity. However, since direct immunization for small molecular natural product is impossible, conjugate synthesis of natural products with carrier protein is necessary at the first step. MAb can be successful obtained by immunization of mice, hybridoma preparation, selection and cloning of hybridoma and culturing. Although high specific MAb in general will be required, wide-cross reactive MAb is also useful for analysis of total related components. Qualitative and quantitative analysis of bioactive natural product is necessary for the quality control of herbal medicines. Immunostaining like eastern blotting can determine and identify bioactive compounds specifically in crude extract resulting in fingerprinting of herb medicine. Compact MAb, Fc-engineered antibody can be used as a neutralized antibody for the plant breeding. A special issues with focus on “Monoclonal Antibody Preparation against Natural Product and Its Application” will review recent developments and application of MAbs against natural products having small molecule and further accelerate the investigation around MAb against natural product.
Prof. Dr. Yukihiro Shoyama
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibodies is an international peer-reviewed Open Access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. For the first couple of issues the Article Processing Charge (APC) will be waived for well-prepared manuscripts. English correction and/or formatting fees of 250 CHF (Swiss Francs) will be charged in certain cases for those articles accepted for publication that require extensive additional formatting and/or English corrections.
- monoclonal antibody
- natural product having small molecule
- quantitative and qualitative analysis
- finger print analysis
- eastern blotting
- immunoaffinity column
- single chain Fv
- Fc-engineered antibody
Antibodies 2012, 1(2), 215-238; doi:10.3390/antib1020215
Received: 10 July 2012; in revised form: 16 August 2012 / Accepted: 21 August 2012 / Published: 29 August 2012| Download PDF Full-text (428 KB) | Download XML Full-text
Review: Fluobodies against Bioactive Natural Products and their Application in Fluorescence-Linked Immunosorbent Assay
Antibodies 2012, 1(2), 239-258; doi:10.3390/antib1020239
Received: 7 August 2012; in revised form: 27 August 2012 / Accepted: 28 August 2012 / Published: 11 September 2012| Download PDF Full-text (1074 KB) | Download XML Full-text
Article: Quality Control System for Beer Developed with Monoclonal Antibodies Specific to Barley Lipid Transfer Protein
Antibodies 2012, 1(3), 259-272; doi:10.3390/antib1030259
Received: 17 September 2012; in revised form: 28 September 2012 / Accepted: 9 October 2012 / Published: 16 October 2012| Download PDF Full-text (607 KB) | Download XML Full-text
Antibodies 2012, 1(3), 273-283; doi:10.3390/antib1030273
Received: 3 September 2012; in revised form: 19 October 2012 / Accepted: 29 October 2012 / Published: 2 November 2012| Download PDF Full-text (249 KB) | Download XML Full-text
Article: Development of Eastern Blotting Technique for Analysis of Baicalin Using Anti-Baicalin Monoclonal Antibody
Antibodies 2012, 1(3), 284-293; doi:10.3390/antib1030284
Received: 31 August 2012; in revised form: 18 November 2012 / Accepted: 22 November 2012 / Published: 27 November 2012| Download PDF Full-text (634 KB) | Download XML Full-text
Antibodies 2012, 1(3), 294-307; doi:10.3390/antib1030294
Received: 28 August 2012; in revised form: 30 November 2012 / Accepted: 4 December 2012 / Published: 6 December 2012| Download PDF Full-text (355 KB) | Download XML Full-text
Communication: Generation of a Monoclonal Antibody Specifically Reacting with Neuron-specific TATA-Box Binding Protein-Associated Factor 1 (N-TAF1)
Antibodies 2013, 2(1), 1-8; doi:10.3390/antib2010001
Received: 9 November 2012; in revised form: 10 December 2012 / Accepted: 14 December 2012 / Published: 21 December 2012| Download PDF Full-text (260 KB) | Download XML Full-text
Last update: 29 October 2012