J — Open Access Journal of Multidisciplinary Science
J (ISSN 2571-8800) is an international, open access journal, published quarterly online. J publishes articles in all research fields. The first issue will be released in 2018.
- Open Access - free for readers, free to re-use.
- Free publication: no APC for well-prepared manuscripts submitted in 2018.
- Peer-Review and Editorial Decision: peer-reviewed manuscripts are carefully evaluated for scientific soundness and correctness by reviewers and accepted/rejected by academic editors. Authors have the option for all reviewer comments and editorial decisions to be published along with the final paper.
- Criteria for Publication:
- Technical correctness and scientific soundness
- Thorough reporting
- Not published elsewhere
- High technical standard and sufficient detail
- Written in an intelligible fashion
- Meets all applicable standards of Research Ethics.
- Rapid Publication: Manuscripts submitted to J are immediately posted on Preprints.org after editorial check. J endeavors to provide a first decision on manuscripts within 15 days from submission. Accepted manuscripts are published online as soon as the production process is complete (copy-editing, English editing, XML conversion and PDF production), generally within 7 days after acceptance (median values for papers published in MDPI journals in 2017).
- Recognition of Reviewers: reviewers who provide timely, thorough peer-review reports receive vouchers entitling them to a discount on the APC of their next publication in any MDPI journal, in appreciation of the work done.
Octyl Gallate as an Intervention Catalyst to Augment Antifungal Efficacy of Caspofungin►▼ Figures
J 2018, 1(1), 4; https://doi.org/10.3390/j1010004 - 23 May 2018
Filamentous fungi such as Aspergillus spp. are opportunistic pathogens, which cause highly invasive infections, especially in immunocompromised individuals. Control of such fungal pathogens is increasingly problematic due to the small number of effective drugs available for treatment. Moreover, the increased incidence of fungal[...] Read more.
Filamentous fungi such as Aspergillus spp. are opportunistic pathogens, which cause highly invasive infections, especially in immunocompromised individuals. Control of such fungal pathogens is increasingly problematic due to the small number of effective drugs available for treatment. Moreover, the increased incidence of fungal resistance to antifungal agents makes this problem a global human health issue. The cell wall integrity system of fungi is the target of antimycotic drugs echinocandins, such as caspofungin (CAS). However, echinocandins cannot completely inhibit the growth of filamentous fungal pathogens, which results in survival/escape of fungi during treatment. Chemosensitization was developed as an alternative intervention strategy, where co-application of CAS with the intervention catalyst octyl gallate (OG; chemosensitizer) greatly enhanced CAS efficacy, thus achieved ≥99.9% elimination of filamentous fungi in vitro. Based on hypersensitive responses of Aspergillus antioxidant mutants to OG, it is hypothesized that, besides destabilizing cell wall integrity, the redox-active characteristic of OG may further debilitate the fungal antioxidant system. Full article
Enhancing Mentorship in Psychiatry and Health Sciences: A Study Investigating Needs and Preferences in the Development of a Mentoring Program►▼ Figures
J 2018, 1(1), 3; https://doi.org/10.3390/j1010003 - 22 March 2018
Preferences for the delivery of department-led mentorship programs are important to understanding and closing the gap between mentorship need and mentorship actualization. The objective of this paper is to, therefore, describe the perceived needs and barriers to mentorship in a postgraduate psychiatry program[...] Read more.
Preferences for the delivery of department-led mentorship programs are important to understanding and closing the gap between mentorship need and mentorship actualization. The objective of this paper is to, therefore, describe the perceived needs and barriers to mentorship in a postgraduate psychiatry program through separate mixed-methods surveys for psychiatry residents and health sciences faculty at a Canadian University. The surveys explored (1) the prevalence of mentorship, (2) barriers to adequate mentorship, and (3) program initiatives that could address these barriers. Qualitative responses were analyzed using an inductive analytic approach. The results of both surveys revealed that while psychiatry residents and faculty believed mentorship to be important for career success, fewer than half of residents (33%) or faculty (47%) reported receiving mentorship in the department. Residents and faculty ranked lack of exposure to mentorship, and lack of time as their top barrier to mentorship, respectively. The following components of a mentorship program were described as ideal: (1) the ability to choose one's own mentor, (2) training sessions for mentors, and (3) faculty mentoring webpage profiles to facilitate the matching of interests. Respondents suggested that mentoring program developers should foster a culture encouraging mentorship, seek mentors outside of regular program-related supervision, allow mentees to choose a mentor, and establishing structure, through aligning expectations and goal setting in mentoring relationships. There is a gap between desire for mentorship and actualization. Program developers in psychiatry medical education may choose to incorporate these findings to enhance mentorship. Full article
Alternative Approaches to the Search for Alzheimer’s Disease Treatments
J 2018, 1(1), 2; https://doi.org/10.3390/j1010002 - 24 February 2018
Clinical trials of drugs for Alzheimer’s disease have called into question the role of amyloid in the disease. The reasons several drugs recently failed clinical trials for Alzheimer’s disease are presented. An alternative approach with a traditional plant medicine is discussed. The pharmacology[...] Read more.
Clinical trials of drugs for Alzheimer’s disease have called into question the role of amyloid in the disease. The reasons several drugs recently failed clinical trials for Alzheimer’s disease are presented. An alternative approach with a traditional plant medicine is discussed. The pharmacology of the phytochemicals found in the plant medicine is provided. Full article
J—A Multidisciplinary Open Access Journal to Accelerate Scientific Communication
J 2018, 1(1), 1; https://doi.org/10.3390/j1010001 - 24 February 2018
30 April 2018
Winners of the First MDPI Writing Prize
Winners of the First MDPI Writing Prize
13 March 2018
MDPI Becoming a Member of UKSG
MDPI Becoming a Member of UKSG
Special Issue in JPharmacology and Clinical Uses of Plant Medicines and Plant Derived Compounds Guest Editor: James Adams
Deadline: 15 October 2018
Special Issue in JResource of Genetic Robustness: Loss-of-Function Mouse Mutant Alleles with no Apparent Phenotype Guest Editors: Florent Hubé, Philip Hublitz, Jean-François Ouimette
Deadline: 15 November 2018
Special Issue in JNanomaterials for Environment: Progress and Future Scopes Guest Editors: Yogendra Mishra, Amit Bhatnagar
Deadline: 30 November 2018