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J. Funct. Biomater. 2017, 8(2), 19; doi:10.3390/jfb8020019

Laser Ablation for Cancer: Past, Present and Future

1
Unit of Measurements and Biomedical Instrumentation, Center for Integrated Research, Università Campus Bio-Medico di Roma, Via Álvaro del Portillo, 21, Rome 00128, Italy
2
IHU (Institute of Image-Guided Surgery), S/c Ircad, Strasbourg 67091, France
3
Department of Surgery, City of Hope, Duarte-Main Campus, 1500 East Duarte Road, Duarte, CA 91010, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Bing Xu
Received: 19 April 2017 / Revised: 30 May 2017 / Accepted: 13 June 2017 / Published: 14 June 2017
(This article belongs to the Special Issue Journal of Functional Biomaterials: Feature Papers 2016)
View Full-Text   |   Download PDF [632 KB, uploaded 15 June 2017]   |  

Abstract

Laser ablation (LA) is gaining acceptance for the treatment of tumors as an alternative to surgical resection. This paper reviews the use of lasers for ablative and surgical applications. Also reviewed are solutions aimed at improving LA outcomes: hyperthermal treatment planning tools and thermometric techniques during LA, used to guide the surgeon in the choice and adjustment of the optimal laser settings, and the potential use of nanoparticles to allow biologic selectivity of ablative treatments. Promising technical solutions and a better knowledge of laser-tissue interaction should allow LA to be used in a safe and effective manner as a cancer treatment. View Full-Text
Keywords: laser ablation; cancer therapy; local cancer therapy; thermal ablation; thermography laser ablation; cancer therapy; local cancer therapy; thermal ablation; thermography
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Schena, E.; Saccomandi, P.; Fong, Y. Laser Ablation for Cancer: Past, Present and Future. J. Funct. Biomater. 2017, 8, 19.

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