Next Article in Journal
Cellular Morphology-Mediated Proliferation and Drug Sensitivity of Breast Cancer Cells
Next Article in Special Issue
Laser Ablation for Cancer: Past, Present and Future
Previous Article in Journal / Special Issue
Enhanced Osseointegration of a Modified Titanium Implant with Bound Phospho-Threonine: A Preliminary In Vivo Study
Article Menu

Export Article

Open AccessFeature PaperArticle
J. Funct. Biomater. 2017, 8(2), 17; doi:10.3390/jfb8020017

The Effect of Platelet-Rich Fibrin, Calcium Sulfate Hemihydrate, Platelet-Rich Plasma and Resorbable Collagen on Soft Tissue Closure of Extraction Sites

1
Department of Periodontics and Endodontics, School of Dental Medicine, University at Buffalo, State University of New York, 250 Squire Hall, Buffalo, NY 14214, USA
2
Department of Periodontology, King Abdulaziz University, University District, Jeddah 22252, Saudi Arabia
*
Author to whom correspondence should be addressed.
Academic Editor: Francesco Puoci
Received: 24 April 2017 / Revised: 16 May 2017 / Accepted: 22 May 2017 / Published: 25 May 2017
(This article belongs to the Special Issue Journal of Functional Biomaterials: Feature Papers 2016)
View Full-Text   |   Download PDF [478 KB, uploaded 25 May 2017]   |  

Abstract

Rapid and complete soft tissue healing after tooth extraction minimizes surgical complications and facilitates subsequent implant placement. We used four treatment methods and assessed changes in soft tissue socket closure following tooth extraction in humans. The effects of platelet-rich fibrin-calcium sulfate hemihydrate (PRF-CSH), platelet-rich plasma-calcium sulfate hemihydrate (PRP-CSH), a resorbable collagen dressing (RCD), and no grafting material were compared in a randomized, controlled pilot study with a blinded parallel design (N = 23). Patients with a hopeless tooth scheduled for extraction were randomly assigned to one of the four treatment groups. Socket measurements were obtained immediately after extraction and treatment, as well as after 21 days. There was a significant decrease in the total epithelialized external surface area of the extraction sockets in each group at all time points. However, there were no significant differences in soft tissue closure (p > 0.05) at any time point and PRF-CSH or PRP-CSH did not provide any additional benefit to enhance the soft tissue closure of extraction sockets compared with either RCD or sites without graft. View Full-Text
Keywords: extraction socket; platelet-rich protein; platelet-rich fibrin; calcium sulfate; soft tissue healing extraction socket; platelet-rich protein; platelet-rich fibrin; calcium sulfate; soft tissue healing
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Yerke, L.M.; Jamjoom, A.; Zahid, T.M.; Cohen, R.E. The Effect of Platelet-Rich Fibrin, Calcium Sulfate Hemihydrate, Platelet-Rich Plasma and Resorbable Collagen on Soft Tissue Closure of Extraction Sites. J. Funct. Biomater. 2017, 8, 17.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
J. Funct. Biomater. EISSN 2079-4983 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top