Next Article in Journal
Cell-Centric View of Apoptosis and Apoptotic Cell Death-Inducing Antitumoral Strategies
Next Article in Special Issue
Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases
Previous Article in Journal
Role of p53 in Cell Death and Human Cancers
Previous Article in Special Issue
Mastic Oil Inhibits the Metastatic Phenotype of Mouse Lung Adenocarcinoma Cells
Cancers 2011, 3(1), 1014-1041; doi:10.3390/cancers3011014
Review

Targets and Mechanisms of Photodynamic Therapy in Lung Cancer Cells: A Brief Overview

,
 and *
Received: 31 December 2010; in revised form: 20 February 2011 / Accepted: 1 March 2011 / Published: 3 March 2011
(This article belongs to the Special Issue Lung Cancer)
View Full-Text   |   Download PDF [373 KB, uploaded 3 March 2011]   |   Browse Figure
Abstract: Lung cancer remains one of the most common cancer-related causes of death. This type of cancer typically develops over a period of many years, and if detected at an early enough stage can be eliminated by a variety of treatments including photodynamic therapy (PDT). A critical discussion on the clinical applications of PDT in lung cancer is well outside the scope of the present report, which, in turn focuses on mechanistic and other aspects of the photodynamic action at a molecular and cellular level. The knowledge of these issues at pre-clinical levels is necessary to develop, check and adopt appropriate clinical protocols in the future. This report, besides providing general information, includes a brief overview of present experimental PDT and provides some non-exhaustive information on current strategies aimed at further improving the efficacy, especially in regard to lung cancer cells.
Keywords: photodynamic therapy; photosensitizers; lung cancer cells photodynamic therapy; photosensitizers; lung cancer cells
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Chiaviello, A.; Postiglione, I.; Palumbo, G. Targets and Mechanisms of Photodynamic Therapy in Lung Cancer Cells: A Brief Overview. Cancers 2011, 3, 1014-1041.

AMA Style

Chiaviello A, Postiglione I, Palumbo G. Targets and Mechanisms of Photodynamic Therapy in Lung Cancer Cells: A Brief Overview. Cancers. 2011; 3(1):1014-1041.

Chicago/Turabian Style

Chiaviello, Angela; Postiglione, Ilaria; Palumbo, Giuseppe. 2011. "Targets and Mechanisms of Photodynamic Therapy in Lung Cancer Cells: A Brief Overview." Cancers 3, no. 1: 1014-1041.


Cancers EISSN 2072-6694 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert