Next Article in Journal
Expression of Mipu1 in Response to Myocardial Infarction in Rats
Next Article in Special Issue
Quantum Dots — Characterization, Preparation and Usage in Biological Systems
Previous Article in Journal
Drosophila melanogaster as a Model Organism of Brain Diseases
Previous Article in Special Issue
Potential Use of Quantum Dots in Flow Cytometry
Article Menu

Export Article

Open AccessReview
Int. J. Mol. Sci. 2009, 10(2), 441-491; doi:10.3390/ijms10020441

Quantum Dots for Live Cell and In Vivo Imaging

University at Albany, Department of Chemistry, 1400 Washington Ave., Albany, NY 12222, USA
*
Author to whom correspondence should be addressed.
Received: 17 December 2008 / Revised: 22 January 2009 / Accepted: 23 January 2009 / Published: 3 February 2009

Abstract

In the past few decades, technology has made immeasurable strides to enable visualization, identification, and quantitation in biological systems. Many of these technological advancements are occurring on the nanometer scale, where multiple scientific disciplines are combining to create new materials with enhanced properties. The integration of inorganic synthetic methods with a size reduction to the nano-scale has lead to the creation of a new class of optical reporters, called quantum dots. These semiconductor quantum dot nanocrystals have emerged as an alternative to organic dyes and fluorescent proteins, and are brighter and more stable against photobleaching than standard fluorescent indicators. Quantum dots have tunable optical properties that have proved useful in a wide range of applications from multiplexed analysis such as DNA detection and cell sorting and tracking, to most recently demonstrating promise for in vivo imaging and diagnostics. This review provides an in-depth discussion of past, present, and future trends in quantum dot use with an emphasis on in vivo imaging and its related applications. View Full-Text
Keywords: Quantum dots; in vivo imaging; applications; biocompatibility; nanoparticles Quantum dots; in vivo imaging; applications; biocompatibility; nanoparticles
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Walling, M.A.; Novak, J.A.; Shepard, J.R.E. Quantum Dots for Live Cell and In Vivo Imaging. Int. J. Mol. Sci. 2009, 10, 441-491.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Int. J. Mol. Sci. EISSN 1422-0067 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top