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Quantum Dots for Live Cell and In Vivo Imaging
Int. J. Mol. Sci. 2009, 10(2), 656-673; doi:10.3390/ijms10020656

Quantum Dots — Characterization, Preparation and Usage in Biological Systems

1,* , 2
1 Department of Microelectronics, Faculty of Electrical Engineering and Communication, Brno University of Technology / Údolní 53, 602 00 Brno, Czech Republic 2 Department of Chemistry and Biochemistry, Faculty of Agronomy, Mendel University of Agriculture and Forestry / Zemědělská 1, 613 00 Brno, Czech Republic
* Author to whom correspondence should be addressed.
Received: 8 January 2009 / Revised: 13 February 2009 / Accepted: 18 February 2009 / Published: 20 February 2009
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The use of fluorescent nanoparticles as probes for bioanalytical applications is a highly promising technique because fluorescence-based techniques are very sensitive. Quantum dots (QDs) seem to show the greatest promise as labels for tagging and imaging in biological systems owing to their impressive photostability, which allow long-term observations of biomolecules. The usage of QDs in practical applications has started only recently, therefore, the research on QDs is extremely important in order to provide safe and effective biosensing materials for medicine. This review reports on the recent methods for the preparation of quantum dots, their physical and chemical properties, surface modification as well as on some interesting examples of their experimental use.
Keywords: Quantum dots; biosensing; biolabeling; template methods; TiO2 Quantum dots; biosensing; biolabeling; template methods; TiO2
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Drbohlavova, J.; Adam, V.; Kizek, R.; Hubalek, J. Quantum Dots — Characterization, Preparation and Usage in Biological Systems. Int. J. Mol. Sci. 2009, 10, 656-673.

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