Reprint

Modulators of Oxidative Stress

Chemical and Pharmacological Aspects

Edited by
November 2020
298 pages
  • ISBN978-3-03943-228-8 (Hardback)
  • ISBN978-3-03943-229-5 (PDF)

This book is a reprint of the Special Issue Modulators of Oxidative Stress: Chemical and Pharmacological Aspects that was published in

Biology & Life Sciences
Summary
The book starts with the editors’ preface summarizing the contributions of each of the following thirteen articles dealing with chemical and pharmacological aspects of the molecular modulators of the oxidative stress in regard to various therapeutic approaches in cardiovascular and neurodegenerative diseases, cancer, and diabetes. The seven articles present data from original research studies enlightening the roles and mechanisms of action of small molecular weight compounds (natural and synthetic; ascorbic acid/vitamin C, deferoxamine, N-acetylcysteine, MitoVitE, α-tocopherol, trolox, and ezetimibe) or proteins (SIRT3) in modulation of oxidative stress. In the six review papers, the authors present and discuss the possible therapeutic potential of novel approaches and compounds that are promising and deserve further investigation, in modulation of oxidative stress.
Format
  • Hardback
License
© 2020 by the authors; CC BY-NC-ND license
Keywords
ascorbic acid; deferoxamine; N-acetylcysteine; ischemia/reperfusion; cardiac fibroblasts; reactive oxygen species; photobiomodulation; reactive oxygen species (ROS); nuclear factor kappa-light-chain-enhancer of activated B cells (NF-кB); cancer; diabetes; wound healing; glucose; pentose phosphate pathway; NADPH; redox balance; glycogen; glycolysis; stress resistance; insulin resistance; immunomodulation; inflammation; olive tree; oxidative stress; secoirioids; sirtuin 3; high fat diet; sex differences; mice; oxidative stress; metabolic stress; antioxidants; ADHD; inflammation; oxidative stress; Nrf2; NRF2-KEAP1; ROS; cancer metabolism; antioxidant; oxidative stress; cancer therapy; chemoresistance; radioresistance; sepsis; MitoVitE; antioxidant; mitochondria; gene expression; cytokines; mRNA; vitamin C; folic acid; one-carbon metabolism; C2C12 cells; metabolomics; mass spectrometry; ascorbic acid; type 2 diabetes; dipeptidyl peptidase-4 inhibitors; biomarkers; oxidative stress; oxidative stress; Nrf2; ER stress; Ezetimibe; ischemia-reperfusion; ionizing radiation; liver; sirtuin 3; hydroperoxide; inflammation; epigenetics; cancer; oxidative stress; miR7/MAFG/Nrf2 axe; chemoresistance; cancer therapy; n/a