Special Issue "Polymer Colloids"
A special issue of Polymers (ISSN 2073-4360).
Deadline for manuscript submissions: 20 January 2014
Dr. Hsing-Lin Wang
C-PCS, Chemistry Division, Los Alamos National Laboratory, Los Alamos, NM 87545, USA
Phone: +1 505 667 9944
Fax: +1 505 667 0851
Interests: polymer synthesis (conjugated polymers and fullerenes); processing and applications of conjugated polymers; polymer nanofibers and colloids; polymer/metal composites; polymeric sensors and actuators; polyeletrolyte (supramolecular) self-assembly
Prof. Dr. Ping Xu
Department of Chemistry, Harbin Institute of Technology, No. 92 West Dazhi St., Nangang Dist., Harbin 150001, China
Phone: +86 451 8641 3702 (ext.812)
Fax: +86 451 8641 8750
Functional polymers possess combined physical, chemical and mechanical properties and functionalities taking advantage of their conductive, optical, electronic and biomedical features. Some functional polymers also reveal stimuli responsive properties that are subject to change upon exposure to external stimuli such as temperature, pH, and light. Perturbation of local environment can lead to change in polymer conformation, structure, and aggregated states that render them be used as smart materials. Polymer colloids allow further expansion of applications of functional polymers as they can be easily processed and adopted for conjugation with a variety of biomolecules. Hierarchical self-assemblies comprised of polymer colloids show applications as photonic materials with tunability simply by changing the size of the colloids. Recent studies also suggest that nanoscaled polymer colloids have similar application potentials as semiconducting quantum dots. In recent years, polymer colloids have emerged as one of the most promising materials due to their size and morphology -dependent properties, and the feasibility for chemical modification that allows exploration of emergent phenomena and commercial applications.
In view of the recent developments in polymer colloids, this specific issue solicits papers relating to the synthesis, processing, self-assembly and applications of polymer colloids and hybrid composites. The topical subjects to be addressed include: micro- and nanoemulsion, polymer complexes, polymer composites, smart materials, chemical modifications, bioconjugates, and correlation between colloid structure and functionality.
Dr. Hsing-Lin Wang
Prof. Dr. Ping Xu
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. Papers will be published continuously (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are refereed through a peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed Open Access quarterly journal published by MDPI.
- synthesis and characterization
- polymer colloids and dispersion
- micro and nanoemulsion
- responsive polymers
- polymer-surfactant complexes
- conjugated polymers
- hybrid polymer colloids (composites)
- functionalization of polymer colloids
- self-assembly of polymer colloids
- biomedical; electronic and optical application
The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.
Type of Paper: Review
Title: Structure and Frictional Property of Gel
Author: Masayuki Tokita
Affiliation: Department of Physics, Faculty of Science, Kyushu University, 6-10-1 Hakozaki, Fukuoka 812-8581, Japan; E-Mail: firstname.lastname@example.org
Abstract: The structure of opaque poly(acrylamide) gel and its frictional property, which is one of the important mechanical properties of the gel, are studied. Both the structure and the friction coefficient of the opaque gel are determined by the independent method. It is found that the friction coefficient of the gel is well explained in terms of the structure of the gel. The relationship between the structure and the frictional property of the gel will be reviewed.
Type of Paper: Article
Title: Preparation of Supramolecular Hydrogels Containing Poloxamers and Methyl beta-cyclodextrin
Authors: Joana Ruivo 1, Rita Oliveira 1,2 and Ana Figueiras 2,3,*
1 Faculdade de Ciências da Saúde, Universidade Fernando Pessoa, Porto, Portugal
2 Centro de Estudos Farmacêuticos, Polo das Ciências da Saúde, Faculdade de Farmácia, Universidade de Coimbra, 3000-548 Coimbra, Portugal
3 Health Sciences Research Centre, University of Beira Interior, Avenida Infante D. Henrique, 6200-506 Covilhã, Portugal
Abstract: Meloxicam (ME) is a non-steroidal anti-inflammatory drug used in the treatment of rheumatoid arthritis, osteoarthritis and other inflammatory diseases. However, its prolonged use is associated to several side effects like gastrointestinal perforations, ulcerations and bleeding, probably due its low aqueous solubility and wettability after oral administration. These side effects can reduce patient compliance and discourage physician from prescribing this drug. In this way, inclusion complexes between meloxicam and methyl-beta-cyclodextrin (ME:MβCD) were prepared in aqueous solution by phase solubility studies and in solid state by freeze-drying method in order to increase drug solubility. The physicochemical characterization of the prepared complexes in solid state was performed by different techniques, namely, differential scanning calorimetry (DSC), infrared spectroscopy (FTIR) and solubility studies. Furthermore, hydrogels containing poloxamers were prepared for topical administration of meloxicam. For this purpose, solid inclusion complexes (ME:MβCD) previously prepared were incorporated in hydrogels with different poloxamers composition. The rheological behaviour of these formulations was studied by different methods (spreadability, viscosity and extrusion) and the drug release from optimized hydrogels was evaluated by Franz diffusion cells, applying some mathematical models to analyse the mechanism of drug release from hydrogels. Results from phase solubility studies show the formation of inclusion complexes between meloxicam and methyl-beta-cyclodextrin in aqueous solution in a stoichiometry 1:1 and an increase in drug solubility. Different techniques employed indicated complete formation of complexes in solid state prepared by the freeze-drying method. Moreover, the performed set of rheological studies, easily adapted to similar systems, demonstrated that hydrogels containing poloxamers and cyclodextrin may provide a suitable supramolecular platform for meloxicam delivery as a novel strategy to increase drug bioavailability.
Keywords: Meloxicam; methyl-β-cyclodextrin; poloxamers; hydrogels; topical delivery
Last update: 16 September 2013