Pharmaceutical Crystallisation Science and Engineering

Dear Colleagues,

Crystallisation plays an essential role in the pharmaceutical industry, in which it is, not only used to isolate and purify Active Pharmaceutical Ingredients (APIs), but also offers a molecular approach to modify APIs in order to achieve desired properties, such as crystal size and shape, polymorphs, solvates, salts, and co-crystals. This requires careful design and optimisation of crystallisation processes. However, a significant gap in the knowledge exists for designing such optimal systems, in particular the relationship between the fundamentals of crystallisation kinetics, i.e., nucleation and crystal growth, with the observed performance and behaviour of the APIs. The aim of this Special Issue of Pharmaceutics journal is to provide a platform to report recent developmentof fundamental knowledge in pharmaceutical crystallisation science and engineering by researchers in the industry and academia from around the world. This Special Issue will focus on the crystallisation fundamentals including nucleation, crystal growth and structure; different types of crystals and their crystallisation environment; crystallisation modelling from molecular to process scales; and industrial crystallisation process development, scale up, measurement and control.

Prof. Dr. Mingzhong Li
Dr. Tariq Mahmud
Guest Editors

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