West Nile Virus Infection

Dear Colleagues,

West Nile virus (WNV) is a mosquito-borne pathogen that belongs to the Flavivirus genus (family Flaviviridae). The virus in maintained in nature in a rural cycle between mosquito vectors, mainly Culex species, and avian hosts. Spillover from this cycle occasionally results in outbreaks in horses and humans. In severe cases the infection can induce neurological signs such as meningitis and encephalitis, and in some case can lead to death. The virus has spread in the world in this century, including its expansion in the Americas since 1999, and an increase in the number of outbreaks and its severity has been observed in Europe in recent years. Considering all these aspects, a multidisciplinary approach including public, animal and environmental health is the best option to increase the knowledge of this problem making this disease an excellent example of “One Health” issue.

In this Special Issue, we invite you to send research papers and reviews related to different aspects of the virus. Topics of interest include (but are not limited to) pathogenesis, vaccines, diagnosis and epidemiology.

Dr. Francisco Llorente
Guest Editor

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