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Pathogens
Special Issues
Anti-HCV Antiviral Treatment
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Anti-HCV Antiviral Treatment

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Viral Pathogens".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 1986

Special Issue Editors

Dr. Carmine Coppola

E-Mail Website
Guest Editor
Department of Hepatology, Gragnano Hospital, 80054 Naples, Italy
Interests: hepatology; infectious disease; ultrasound; liver transplant
Dr. Federica Pisano

E-Mail Website
Guest Editor
Department of Hepatology, Gragnano Hospital, 80054 Naples, Italy
Interests: diabetes; hepatology; ultrasound

Special Issue Information

Dear Colleagues,

The fight against hepatitis C has marked a turning point in medical history but is still an open challenge. Objective: elimination!

This special issue, published by journal “Pathogens”, aims to be a collection of experiences and future stragegies-sharing.

What suggestions can we take from this pandemic? What we have learned from this pandemic? We will try to answer these questions together.

We invite our colleagues from Internal medicine, infectious diseases, gastroenterology, epidemiology, including clinical and basic research, to contribute their manuscripts for publication review in this Special Issue of the journal dedicated to our common enemy.

Dr. Carmine Coppola
Dr. Federica Pisano
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • microelimination
  • HCV treatment
  • screening
  • public health
  • hepatitis C virus

Published Papers (1 paper)

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Research

9 pages, 686 KiB  
Article
Hepatitis C Virus Micro-Elimination Plan in Southern Italy: The “HCV ICEberg” Project
by Carmine Coppola, Loreta A. Kondili, Laura Staiano, Simona Cammarota, Anna Citarella, Mirko Pio Aloisio, Angelo Annunziata, Francesca Futura Bernardi, Aldo D’Avino, Michele D’Orazio, Marianna Fogliasecca, Mario Fusco, Federica Pisano, Adriano Vercellone, Elvira Bianco and Ugo Trama
Pathogens 2023, 12(2), 195; https://doi.org/10.3390/pathogens12020195 - 28 Jan 2023
Cited by 4 | Viewed by 1666
Abstract
This study evaluates the feasibility of a local action program for HCV micro-elimination in highly endemic areas. Retrospective analysis: administrative and laboratory data (Local Health Unit, southern Italy) were integrated to quantize the anti-HCV-positive subjects not RNA tested and untreated HCV-infected subjects (2018–2022). [...] Read more.
This study evaluates the feasibility of a local action program for HCV micro-elimination in highly endemic areas. Retrospective analysis: administrative and laboratory data (Local Health Unit, southern Italy) were integrated to quantize the anti-HCV-positive subjects not RNA tested and untreated HCV-infected subjects (2018–2022). Prospective analysis: all subjects admitted to a division of the LHU largest hospital (2021–2022) were tested for HCV, with linkage of active-infected patients to care. Overall, 49287 subjects were HCV-Ab tested: 1071 (2.2%) resulted positive without information for an HCV RNA test and 230 (0.5%) had an active infection not yet cured. Among 856 admitted subjects, 54 (6.3%) were HCV-Ab+ and 27 (3.0%) HCV RNA+. Of HCV-infected patients, 22.2% had advanced liver disease, highlighting the need for earlier diagnosis; 27.7% were unaware of HCV infection; and 20.4% were previously aware but never referred to a clinical center. Of these, 26% died and 74% received treatment. Our study emphasizes the value of an active HCV hospital case-finding program to enhance diagnosis in patients with several comorbidities and to easily link them to care. Our data strongly suggest extending this program to all hospital wards/access as a standard of care, particularly in highly endemic areas, to help HCV disease control and take steps in achieving the elimination goals. Full article
(This article belongs to the Special Issue Anti-HCV Antiviral Treatment)
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