Effects of Dietary Polyphenols on Immune System

Dear Colleagues,

Bioactive compounds, such as polyphenols, are found in small quantities in foods of plant origin such as fruits, vegetables, and whole grains. The consumption of these bioactive compounds not only provides basic nutritional benefits but also has been shown to have beneficial effects on health, including physiological, metabolic, and immunological aspects, thus playing an important role in preventing various diseases. In this regard, their antioxidant activity can diminish the risk of numerous diseases, such as cancer, cardiovascular diseases, Alzheimer’s, diabetes, cataract, and age-related dementia, among others. Among their mechanisms of action, the stimulation of the defense mechanism, the reinforcement of the repair process, or even the prevention of widespread damage have been reported. Overall, the immunomodulation by these bioactive compounds represents a promising preventive or therapeutic strategy against several pathological processes, and further knowledge about their ability to modulate both the functionality and composition of the immune system is needed.

In this regard, this Special Issue of Nutrients will focus on the relevant knowledge of the impact of dietary polyphenols on the immune system and the microbiota to provide the most recent perspectives of this area. Papers in the form of original in vitro, clinical, and preclinical studies as well as review articles are welcome for submission.

Dr. Malen Massot-Cladera
Dr. Garyfallia Kapravelou
Guest Editors

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• immune system
• gut microbiota
• immunonutrition
• polyphenols
• phenolic compounds
• flavonoids
• lignans
• stilbenes
• carotenoids
• anthocyanins
• polyphenol-enriched foods
• functional foods
• fruits
• vegetables
• antioxidants