Freeze-Dried Plasma for Major Trauma: Trends and Applications
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: closed (20 September 2024) | Viewed by 2050
Special Issue Editors
Interests: hemostatic agents; thromboelastometry; trauma coagulopathy; bio-mathematical modeling
2. Royal Canadian Medical Services, Ottawa, K1A 0K2, Canada
Interests: massive transfusion; freeze-dried plasma; trauma resuscitation and databases
Special Issue Information
Dear Colleague,
Hemorrhage, frequently complicated by coagulopathy, remains the leading cause of preventable deaths in both civilian and military trauma. There has been an increasing emphasis on hemostatic resuscitation with blood products at the earliest possible time after injury. Given its benefits in reducing blood loss and mortality, and its long storage stability at ambient temperature, high portability, and fast reconstitution for transfusion in an austere field environment, freeze-dried plasma (FDP) is a promising alternative to fresh frozen plasma (FFP) for hemostatic resuscitation in the prehospital settings. Both laboratory and clinical studies have been conducted to show the potential logistic, strategic advantages and therapeutic benefits of FDP as a sufficient blood supply for resuscitation of severely bleeding trauma patients in far-forward military operations and civilian mass-casualty events. The present Special Issue, edited by Drs. Henry Peng, Andrew Beckett and Luis da Luz, disseminate a collection of papers on various topics, including the history, recent advances, and future development of freeze-dried plasma for major trauma.
Dr. Henry Peng
Dr. Andrew Neil Beckett
Dr. Luis da Luz
Guest Editors
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Keywords
- blood products
- blood transfusion
- coagulation
- freeze-dried plasma
- fresh frozen plasma
- hemorrhage
- hemorrhagic shock
- hemostatic agent
- hemostatic resuscitation
- major trauma
- massive transfusion
- prehospital resuscitation
- trauma coagulopathy
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