Biomaterials in Bone Reconstruction

Dear colleagues,

This Special Issue aims to focus on the current status and recent advances in biomaterials for bone reconstruction. Natural bone is a complex tissue vital for structural support, organ protection and mobility. Bone defects, especially complicated or large-scale lesions resulting from tumors, trauma, infection or other damages, are still a challenging issue. To improve the reconstruction of the damaged bones, tissue engineering has been introduced as a promising approach. Artificial bone must have sufficient mechanical and excellent biological properties. Bioengineered composite scaffolds consisting of multifunctional biomaterials with cells, growth factors and bioactive therapeutic agents have great promise for bone reconstruction. Smart stimulus-responsive materials have recently been researched to facilitate non-invasive and controllable dynamic repair or bone defects with the help of electrical, optical, ultrasound and thermal stimuli related to external physical triggers or disease microenvironments. To mimic the original structure of bone tissue, gradient porous scaffold structures were designed in the lattice form, truss structures and triply periodic minimal surface structures. Additionally, three-dimensional (3D) printing technologies  allow for the specific fabrication of scaffolds with an appropriate size, shape and intrinsic structures. Considering the pivotal role of bone tissue, this Special Issue seeks innovative strategies to promote bone defect repair and regeneration.

Dr. Liya Zhu
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Functional Biomaterials is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• biomaterials
• tissue engineering
• porous scaffold
• 3D printing
• bone regeneration