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Journal of Functional Biomaterials, Volume 15, Issue 5

2024 May - 24 articles

Cover Story: Advancements in imaging, particularly high-speed imaging with a 100 kHz frame rate, have aided spray visualization analysis. This technique allows for the investigation of the impact of nozzle design on spray distribution, particularly regarding droplet size, particle number, and surface coverage. Analyzing these factors provides deeper insights into how nozzles influence cell behavior and how this can impact cell spray treatments for burn wounds. Efficient cell delivery and complete wound coverage are crucial for success, and investigating nozzle design through high-speed imaging analysis can significantly improve these outcomes. View this paper
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Articles (24)

  • Article
  • Open Access
10 Citations
7,358 Views
13 Pages

Skin and soft tissue reconstruction has long been based on the reconstructive ladder. However, a skin substitute has become popular due to its predictable outcomes, without donor-site morbidity. The biodegradable temporizing matrix (BTM; NovoSorb, Po...

(This article belongs to the Section Biomaterials for Tissue Engineering and Regenerative Medicine)
  • Article
  • Open Access
11 Citations
4,121 Views
17 Pages

In Silico Evaluation of In Vivo Degradation Kinetics of Poly(Lactic Acid) Vascular Stent Devices

  • Shicheng He,
  • Lingling Wei,
  • Guixue Wang,
  • Nicola M. Pugno,
  • Qiang Chen and
  • Zhiyong Li

Biodegradable vascular stents (BVS) are deemed as great potential alternatives for overcoming the inherent limitations of permanent metallic stents in the treatment of coronary artery diseases. The current study aimed to comprehensively compare the m...

  • Article
  • Open Access
8 Citations
4,275 Views
20 Pages

This study aimed to assess the adaptability and penetration depth capacity of recent bioceramic systems, including regular EndoSequence (BC) versus HiFlow (BCH) sealers in the presence of BC points. A total of 54 single-rooted teeth were instrumented...

(This article belongs to the Section Dental Biomaterials)
  • Article
  • Open Access
10 Citations
4,514 Views
14 Pages

The aim of this study is to analyze the resorption rate of bone graft materials after crestal sinus floor elevation, study its influencing factors, and improve the long-term success rate of implants after crestal maxillary sinus floor elevation. Meas...

(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—2nd Edition)
  • Systematic Review
  • Open Access
16 Citations
7,466 Views
25 Pages

Effect of Different Irrigating Solutions on Root Canal Dentin Microhardness—A Systematic Review with Meta-Analysis

  • Sunidhi Agarwal,
  • Lora Mishra,
  • Naomi Ranjan Singh,
  • Rini Behera,
  • Manoj Kumar,
  • Ravishankar Nagaraja,
  • Krzysztof Sokolowski and
  • Barbara Lapinska

The aim of this study was to evaluate the effect of different irrigating solutions as well as their combination and activation modes on root canal dentin microhardness. The protocol was registered in PROSPERO and PRISMA guidelines were followed. The...

(This article belongs to the Special Issue Biomaterials in Restorative Dentistry and Endodontics)
  • Review
  • Open Access
23 Citations
15,926 Views
15 Pages

There is a vast amount of published literature concerning dental veneers; however, the effects of tooth preparation, aging, veneer type, and resin cement type on the failure of dental veneers in laboratory versus clinical scenarios are not clear. The...

(This article belongs to the Section Dental Biomaterials)
  • Article
  • Open Access
4 Citations
2,294 Views
11 Pages

This study aimed to compare the impact of CAD/CAM closed systems and open systems on the marginal gap of monolithic zirconia-reinforced lithium silicate (ZLS) ceramic crowns, as both systems are used in everyday dentistry, both chair-side and laborat...

  • Article
  • Open Access
4 Citations
2,717 Views
23 Pages

Preparation and In Vitro Characterization of Lactococcus lactis-Loaded Alginate Particles as a Promising Delivery Tool for Periodontal Probiotic Therapy

  • Bettina Wuttke,
  • Katharina Ekat,
  • Oleksandra Chabanovska,
  • Mario Jackszis,
  • Armin Springer,
  • Praveen Vasudevan,
  • Bernd Kreikemeyer and
  • Hermann Lang

Probiotic microorganisms are used in a variety of food supplements and medical formulations to promote human health. In periodontal therapy, probiotics are mainly used in the form of gels, tablets or rinses that often tend to leak from the periodonta...

(This article belongs to the Special Issue Advanced Biomaterials for Periodontal Regeneration)
  • Article
  • Open Access
4 Citations
2,378 Views
19 Pages

(1) Background: currently, the advantages of bulk-fill resin composite and high-viscosity glass ionomer materials have increased their use in dentistry; accordingly, their mechanical, surface, and optical properties have become more important. This s...

(This article belongs to the Section Dental Biomaterials)
  • Article
  • Open Access
5 Citations
2,786 Views
17 Pages

Nano-adjuvant vaccines could induce immune responses and enhance immunogenicity. However, the application and manufacturing of nano-adjuvant is hampered by its challenging scale-up, poor reproducibility, and low security. Therefore, the present study...

(This article belongs to the Special Issue Nanoparticles and Nanocompounds for Cancer Therapy)
  • Article
  • Open Access
2 Citations
2,208 Views
16 Pages

High-Speed Fluorescence Imaging Corroborates Biological Data on the Influence of Different Nozzle Types on Cell Spray Viability and Formation

  • Miriam Heuer,
  • Mehdi Stiti,
  • Volker Eras,
  • Julia Scholz,
  • Norus Ahmed,
  • Edouard Berrocal and
  • Jan C. Brune

Treating severe dermal disruptions often presents significant challenges. Recent advancements have explored biological cell sprays as a promising treatment, but their success hinges on efficient cell delivery and complete wound coverage. This require...

(This article belongs to the Special Issue Biomaterials in Medical Diagnosis and Treatment)
  • Article
  • Open Access
13 Citations
4,713 Views
9 Pages

Effect of Bleaching on Resin-Infiltration-Masked Artificial White Spots In Vitro

  • Alan Leon Sinanovic,
  • Philipp Messer-Hannemann,
  • Mariam Samadi,
  • Falk Schwendicke and
  • Susanne Effenberger

Resin infiltration is an effective method to mask vestibular white spots. If needed, external bleaching is usually recommended before infiltration, whilst in clinical practice, this sequence may not always be feasible. This in vitro study evaluated t...

(This article belongs to the Section Dental Biomaterials)
  • Article
  • Open Access
10 Citations
2,941 Views
16 Pages

Use of Local Melatonin with Xenogeneic Bone Graft to Treat Critical-Size Bone Defects in Rats with Osteoporosis: A Randomized Study

  • Karen Laurene Dalla Costa,
  • Letícia Furtado Abreu,
  • Camila Barreto Tolomei,
  • Rachel Gomes Eleutério,
  • Rosanna Basting,
  • Gabriela Balbinot,
  • Fabrício Mezzomo Collares,
  • Pedro Lopes,
  • Nelio Veiga and
  • Daiane Cristina Peruzzo
  • + 1 author

The aim of this study was to evaluate the effect of local administration of melatonin (MLT) on molecular biomarkers and calvaria bone critical defects in female rats with or without osteoporosis, associated or not with a xenogeneic biomaterial. Forty...

  • Systematic Review
  • Open Access
12 Citations
4,357 Views
15 Pages

Structural and Color Alterations of Teeth following Orthodontic Debonding: A Systematic Review

  • Francesco Inchingolo,
  • Angelo Michele Inchingolo,
  • Lilla Riccaldo,
  • Roberta Morolla,
  • Roberta Sardano,
  • Daniela Di Venere,
  • Andrea Palermo,
  • Alessio Danilo Inchingolo,
  • Gianna Dipalma and
  • Massimo Corsalini

Aim: The objective of this study was to explore the effects of fixed orthodontic appliances on enamel structure by assessing microfractures, surface roughness, and alterations in color. Methods: This review followed the Preferred Reporting Items for...

(This article belongs to the Special Issue Advanced Materials and Technologies in Orthodontics)
  • Article
  • Open Access
7 Citations
2,841 Views
16 Pages

Fracture Resistance of a Bone-Level Two-Piece Zirconia Oral Implant System—The Influence of Artificial Loading and Hydrothermal Aging

  • Ralf J. Kohal,
  • Ellen Riesterer,
  • Kirstin Vach,
  • Sebastian B. M. Patzelt,
  • Aljaž Iveković,
  • Lara Einfalt,
  • Andraž Kocjan and
  • Anna-Lena Hillebrecht

Preclinical and clinical research on two-piece zirconia implants are warranted. Therefore, we evaluated the in vitro fracture resistance of such a zirconia oral implant system. The present study comprised 32 two-piece zirconia implants and abutments...

(This article belongs to the Special Issue Advanced Biomaterials and Oral Implantology—2nd Edition)
  • Correction
  • Open Access
1,277 Views
2 Pages

Correction: Omori et al. Sinus Mucosal Damage Triggered by Synthetic or Xenogeneic Bone Substitutes: A Histological Analysis in Rabbits. J. Funct. Biomater. 2022, 13, 257

  • Yuki Omori,
  • Daniele Botticelli,
  • Stefano Migani,
  • Vitor Ferreira Balan,
  • Eduardo Pires Godoy and
  • Samuel Porfirio Xavier

In the original publication [...]

(This article belongs to the Special Issue Bone Regeneration and Repair Materials)
  • Article
  • Open Access
12 Citations
4,022 Views
14 Pages

Design of Multi-Functional Bio-Safe Dental Resin Composites with Mineralization and Anti-Biofilm Properties

  • Jiaojiao Yun,
  • Michael F. Burrow,
  • Jukka P. Matinlinna,
  • Hao Ding,
  • Sin Man (Rosalind) Chan,
  • James K. H. Tsoi and
  • Yan Wang

This study aims to develop multi-functional bio-safe dental resin composites with capabilities for mineralization, high in vitro biocompatibility, and anti-biofilm properties. To address this issue, experimental resin composites consisting of UDMA/TE...

(This article belongs to the Section Dental Biomaterials)
  • Article
  • Open Access
14 Citations
5,982 Views
21 Pages

Investigating Bioactive-Glass-Infused Gels for Enamel Remineralization: An In Vitro Study

  • Zbigniew Raszewski,
  • Katarzyna Chojnacka and
  • Marcin Mikulewicz

Objective: Dental hypersensitivity remains widespread, underscoring the need for materials that can effectively seal dental tubules. This study evaluated the potential of bioactive-glass-infused hydroxyethyl cellulose gels in this context. Methods: F...

(This article belongs to the Special Issue Technologies and Materials for Application in Dental, Oral and Maxillofacial Engineering)
  • Article
  • Open Access
6 Citations
3,590 Views
17 Pages

Resorbable Patient-Specific Implants of Molybdenum for Pediatric Craniofacial Surgery—Proof of Concept in an In Vivo Pilot Study

  • Dominik Thomas Hoppe,
  • André Toschka,
  • Nadia Karnatz,
  • Henriette Louise Moellmann,
  • Maximilian Seidl,
  • Lutz van Meenen,
  • Georg Poehle,
  • Christian Redlich and
  • Majeed Rana

Titanium continues to be the gold standard in the field of osteosynthesis materials. This also applies to pediatric craniofacial surgery. Various resorbable materials have already been developed in order to avoid costly and risky second operations to...

(This article belongs to the Special Issue Functional Composites for Bone Implants and Osseointegration)
  • Article
  • Open Access
7 Citations
3,073 Views
25 Pages

Cargo encapsulation through emulsion-based methods has been pondered over the years. Although several microemulsification techniques have been employed for the microcapsule’s synthesis, there are still no clear guidelines regarding the suitabil...

(This article belongs to the Special Issue State of the Art in Biomaterials for Drug Delivery)
  • Article
  • Open Access
5 Citations
3,757 Views
21 Pages

Cell Instructive Behavior of Composite Scaffolds in a Co-Culture of Human Mesenchymal Stem Cells and Peripheral Blood Mononuclear Cells

  • Georgia-Ioanna Kontogianni,
  • Amedeo Franco Bonatti,
  • Carmelo De Maria,
  • Raasti Naseem,
  • Catarina Coelho,
  • Kalliopi Alpantaki,
  • Aristea Batsali,
  • Charalampos Pontikoglou,
  • Paulo Quadros and
  • Maria Chatzinikolaidou
  • + 3 authors

The in vitro evaluation of 3D scaffolds for bone tissue engineering in mono-cultures is a common practice; however, it does not represent the native complex nature of bone tissue. Co-cultures of osteoblasts and osteoclasts, without the addition of st...

  • Article
  • Open Access
9 Citations
3,556 Views
13 Pages

This study aimed to analyze the effect of the height of the proximal axial wall of the prepared tooth and the distance between the adjacent tooth and the prepared tooth on the scan accuracy of intraoral scanners. Ten working casts with maxillary firs...

(This article belongs to the Special Issue Functional Biomaterials and Digital Technologies in Dentistry: From Bench to Bedside—2nd Edition)
  • Article
  • Open Access
2 Citations
3,054 Views
17 Pages

Titanium with apatite-forming ability as well as antibacterial activity is useful as a component of antibacterial dental implants. When Ti was subjected to hydrogen peroxide (H2O2), copper acetate (Cu(OAc)2), and heat (H2O2-Cu(OAc)2-heat) treatments,...

(This article belongs to the Special Issue Active Biomedical Materials and Their Applications)
  • Article
  • Open Access
14 Citations
4,208 Views
18 Pages

Hydrogels and Carbon Nanotubes: Composite Electrode Materials for Long-Term Electrocardiography Monitoring

  • Leszek Kolodziej,
  • Olga Iwasińska-Kowalska,
  • Grzegorz Wróblewski,
  • Tomasz Giżewski,
  • Małgorzata Jakubowska and
  • Agnieszka Lekawa-Raus

This paper presents methods for developing high-performance interface electrode materials designed to enhance signal collection efficacy during long-term (over 24 h) electrocardiography (ECG) monitoring. The electrode materials are fabricated by inte...

(This article belongs to the Section Biomaterials and Devices for Healthcare Applications)
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J. Funct. Biomater. - ISSN 2079-4983