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Clinical Frontiers in Cardiogenic Shock
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Clinical Frontiers in Cardiogenic Shock

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: closed (20 November 2022) | Viewed by 4641

Special Issue Editor

Prof. Dr. Shemy Carasso

E-Mail Website
Guest Editor
1. Division of Cardiovascular Medicine, B Padeh Medical Center, Poriya, Lower Galilee, Israel
2. The Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel
Interests: digital cardiac imaging; echocardiography; CT; MRI; myocardial mechanics; valve diseases; heart failure; cardiomyopathies

Special Issue Information

Dear colleagues,

Despite all advances, cardiogenic shock syndrome (CSS) is a multidisciplinary challenge in its diagnosis, monitoring and management, resulting in a high rate of mortality (exceeding 40%). During the current COVID-19 pandemic, CSS management has become crucial as a major aspect of the multi-organ failure associated with this disease, with major controversies regarding the triage, monitoring, drug, and the place and timing of device therapy (mechanical circulatory support).  Moreover, the presence of CSS along with other causes of shock—such as sepsis or anaphylaxis—causes the understanding of hemodynamics and treatment selection to be more complex.

This Special Issue of the Journal of Clinical Medicine, called “Clinical Frontiers in Cardiogenic Shock”, will focus on new advances in triage, protocols, advances in monitoring and new drugs and device therapies.

Prof. Dr. Shemy Carasso
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • shock
  • heart failure
  • mechanical circulatory support
  • ECMO
  • point-of-care ultrasound (POCUS)
  • catecholamines
  • phosphodiesterase inhibitors
  • acute coronary syndrome
  • acute aortic syndrome
  • valvular heart disease

Published Papers (3 papers)

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Editorial

Jump to: Research, Review

4 pages, 189 KiB  
Editorial
The Battle against Cardiogenic Shock
by Eldad Rahamim, Shemy Carasso, Offer Amir and Gabby Elbaz-Greener
J. Clin. Med. 2022, 11(23), 6958; https://doi.org/10.3390/jcm11236958 - 25 Nov 2022
Viewed by 763
Abstract
Cardiogenic shock (CS) is a life-threatening condition characterized by hypoperfusion and hypoxia caused by low cardiac output [...] Full article
(This article belongs to the Special Issue Clinical Frontiers in Cardiogenic Shock)

Research

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13 pages, 3507 KiB  
Article
Artificial Intelligence (AI) versus POCUS Expert: A Validation Study of Three Automatic AI-Based, Real-Time, Hemodynamic Echocardiographic Assessment Tools
by Eyal Gohar, Amit Herling, Mor Mazuz, Gal Tsaban, Tomer Gat, Sergio Kobal and Lior Fuchs
J. Clin. Med. 2023, 12(4), 1352; https://doi.org/10.3390/jcm12041352 - 8 Feb 2023
Cited by 9 | Viewed by 2306
Abstract
Background: Point Of Care Ultra-Sound (POCUS) is an operator dependent modality. POCUS examinations usually include ‘Eyeballing’ the inspected anatomical structure without conducting accurate measurements due to complexity and insufficient time. Automatic real time measuring tools can make accurate measurements fast and simple and [...] Read more.
Background: Point Of Care Ultra-Sound (POCUS) is an operator dependent modality. POCUS examinations usually include ‘Eyeballing’ the inspected anatomical structure without conducting accurate measurements due to complexity and insufficient time. Automatic real time measuring tools can make accurate measurements fast and simple and dramatically increase examination reliability while saving the operator much time and effort. In this study we aim to assess three automatic tools which are integrated into the Venue™ device by GE: the automatic ejection fraction, velocity time integral, and inferior vena cava tools in comparison to the gold standard—an examination by a POCUS expert. Methods: A separate study was conducted for each of the three automatic tools. In each study, cardiac views were acquired by a POCUS expert. Relevant measurements were taken by both an auto tool and a POCUS expert who was blinded to the auto tool’s measurement. The agreement between the POCUS expert and the auto tool was measured for both the measurements and the image quality using a Cohen’s Kappa test. Results: All three tools have shown good agreement with the POCUS expert for high quality views: auto LVEF (0.498; p < 0.001), auto IVC (0.536; p = 0.009), and the auto VTI (0.655; p = 0.024). Auto VTI has also shown a good agreement for medium quality clips (0.914; p < 0.001). Image quality agreement was significant for the auto EF and auto IVC tools. Conclusions: The Venue™ show a high agreement with a POCUS expert for high quality views. This shows that auto tools can provide reliable real time assistance in performing accurate measurements, but do not reduce the need of a good image acquisition technique. Full article
(This article belongs to the Special Issue Clinical Frontiers in Cardiogenic Shock)
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Review

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14 pages, 571 KiB  
Review
Mechanical Circulatory Support Devices for the Treatment of Cardiogenic Shock Complicating Acute Myocardial Infarction—A Review
by Sharon Bruoha, Chaim Yosefy, Louay Taha, Danny Dvir, Mony Shuvy, Rami Jubeh, Shemy Carasso, Michael Glikson and Elad Asher
J. Clin. Med. 2022, 11(17), 5241; https://doi.org/10.3390/jcm11175241 - 5 Sep 2022
Cited by 8 | Viewed by 3375
Abstract
Cardiogenic shock complicating acute myocardial infarction is a complex clinical condition associated with dismal prognosis. Routine early target vessel revascularization remains the most effective treatment to substantially improve outcomes, but mortality remains high. Temporary circulatory support devices have emerged with the aim to [...] Read more.
Cardiogenic shock complicating acute myocardial infarction is a complex clinical condition associated with dismal prognosis. Routine early target vessel revascularization remains the most effective treatment to substantially improve outcomes, but mortality remains high. Temporary circulatory support devices have emerged with the aim to enhance cardiac unloading and improve end-organ perfusion. However, quality evidence to guide device selection, optimal installation timing, and post-implantation management are scarce, stressing the importance of multidisciplinary expert care. This review focuses on the contemporary use of short-term support devices in the setting of cardiogenic shock following acute myocardial infarction, including the common challenges associated this practice. Full article
(This article belongs to the Special Issue Clinical Frontiers in Cardiogenic Shock)
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