Skin Rehabilitation: Recent Advances and Future Perspectives

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Plastic, Reconstructive and Aesthetic Surgery/Aesthetic Medicine".

Deadline for manuscript submissions: 31 August 2024 | Viewed by 2784

Special Issue Editors


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Guest Editor
Hand Surgery Unit Director, Plastic and Reconstructive Surgery Department, Soroka University Medical Center and the Faculty of Health Sciences, Ben Gurion University of the Negev Beer Sheba 84105, Israel
Interests: skin; hand; plastic and reconstructive surgery; microsurgery
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Guest Editor
1. Plastic Surgery Department and Burn Unit, Soroka University Medical Center, Beer Sheba 84101, Israel
2. Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheba 84105, Israel
Interests: burns; wounds; plastic surgery; burn units; microsurgery; wound dressings; cosmetic surgery; hand surgery; software validation; plastic and reconstructive surgery

Special Issue Information

Dear Colleagues,

Skin rehabilitation is a rapidly developing field that is focused on improving the function and appearance of damaged skin. Recent advances in skin rehabilitation have led to the development of new treatments for a variety of skin conditions, including burns, wounds, and scars.

Amongst others, some of the recent advances in skin rehabilitation include: the use of stem cells, the use of biomaterials that are designed to mimic the properties of natural tissues to provide a scaffold for new tissue growth or to deliver drugs or growth factors to the skin, the development of new wound dressings that promote healing and prevent infection, the use of lasers to treat scars and other skin blemishes, the development of new surgical techniques for skin grafting and reconstruction, and the use of gene therapy to treat skin diseases.

The future of skin rehabilitation is promising. With continued research, new and improved treatments will be developed that will help people with damaged skin regain their quality of life.

Dr. Yuval Krieger
Dr. Yaron Shoham
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • skin rehabilitation
  • stem cells
  • biomaterials
  • growth factors
  • drug delivery
  • wound healing
  • burn care
  • scar management

Published Papers (1 paper)

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Review

13 pages, 3990 KiB  
Review
Needle-Free Jet Injection of Poly-(Lactic Acid) for Atrophic Acne Scars: Literature Review and Report of Clinical Cases
by Nark-Kyoung Rho, Hyun-Jo Kim, Hyun-Seok Kim and Won Lee
J. Clin. Med. 2024, 13(2), 440; https://doi.org/10.3390/jcm13020440 - 13 Jan 2024
Cited by 1 | Viewed by 2529
Abstract
Acne scars, particularly atrophic ones, present a persistent challenge in cosmetic medicine and surgery, requiring extended and multifaceted treatment approaches. Poly-(lactic acid) injectable fillers show promise in managing atrophic acne scars by stimulating collagen synthesis. However, the utilization of needle-free injectors for delivering [...] Read more.
Acne scars, particularly atrophic ones, present a persistent challenge in cosmetic medicine and surgery, requiring extended and multifaceted treatment approaches. Poly-(lactic acid) injectable fillers show promise in managing atrophic acne scars by stimulating collagen synthesis. However, the utilization of needle-free injectors for delivering poly-(lactic acid) into scars remains an area requiring further exploration. In this article, a summary of the latest advancements in needle-free jet injectors is provided, specifically highlighting the variations in jet-producing mechanisms. This summary emphasizes the differences in how these mechanisms operate, offering insights into the evolving technology behind needle-free injection systems. The literature review revealed documented cases focusing on treating atrophic acne scars using intralesional poly-(lactic acid) injections. The results of these clinical studies could be supported by separate in vitro and animal studies, elucidating the feasible pathways through which this treatment operates. However, there is limited information on the use of needle-free jet injectors for the intradermal delivery of poly-(lactic acid). Clinical cases of atrophic acne scar treatment are presented to explore this novel treatment concept, the needle-free delivery of poly-(lactic acid) using a jet pressure-based injector. The treatment demonstrated efficacy with minimal adverse effects, suggesting its potential for scar treatment. The clinical efficacy was supported by histological evidence obtained from cadaver skin, demonstrating an even distribution of injected particles in all layers of the dermis. In conclusion, we suggest that novel needle-free injectors offer advantages in precision and reduce patient discomfort, contributing to scar improvement and skin rejuvenation. Further comprehensive studies are warranted to substantiate these findings and ascertain the efficacy of this approach in scar treatment on a larger scale. Full article
(This article belongs to the Special Issue Skin Rehabilitation: Recent Advances and Future Perspectives)
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