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Advancements and Challenges in Retina Surgery
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Advancements and Challenges in Retina Surgery

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Ophthalmology".

Deadline for manuscript submissions: 25 September 2024 | Viewed by 774

Special Issue Editors

Dr. Joaquín Marticorena

E-Mail Website
Guest Editor
Ophthalmology Department, Hospital Provincial de Conxo, University Hospital Complex of Santiago de Compostela, Rúa Ramón Baltar, Santiago de Compostela, Spain
Interests: vitreoretinal surgery; medical retina; ocular trauma; uvel melanoma; cataract surgery
Dr. Cristina Irigoyen

E-Mail Website
Guest Editor
Department of Ophthalmology, Donostia University Hospital (HUD), Donostia San-Sebastián, Spain
Interests: retinal dystrophies; retinal disease
Dr. Javier Zarranz-Ventura

E-Mail Website
Guest Editor
Institut Clínic of Ophthalmology (ICOF), Hospital Clínic, Barcelona, Spain
Interests: retinal care; intravitreal injection
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Over the last decade, retinal specialists have contributed to important advances in the management of different vitreoretinal diseases. This knowledge, accumulated from basic and clinical studies, has arised in conjunction with the development of new technologies. In this context, multimodal imaging has led to a significant improvement in the diagnosis, understanding and classification of already-known pathologies, as well as the description of new entities. Moreover, the presence of small-gauge vitreotomes with ultra-high-speed cut rates, microscopes with incorporated OCT together with the possibility of administering different drugs and therapies in the vitreous cavity, subretinal and suprachoroidal spaces have revolutionized vitreoretinal surgery, paving a road to treat more complex and challenging cases in a safer manner.

This Special Issue aims to publish original articles that guide ophthalmologists in the surgical treatment of vitreoretinal diseases. Submissions of review articles of high interest are welcome.

Dr. Joaquín Marticorena
Dr. Cristina Irigoyen
Dr. Javier Zarranz-Ventura
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • retina
  • vitreoretinal diseases
  • vitreotomes
  • optical coherence tomography
  • vitreoretinal surgery

Published Papers (2 papers)

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Research

15 pages, 2087 KiB  
Article
Quantitative Microvascular Change Analysis Using a Semi-Automated Software in Macula-off Rhegmatogenous Retinal Detachment Assessed by Swept-Source Optical Coherence Tomography Angiography
by Pablo Díaz-Aljaro, Javier Zarranz-Ventura, Laura Broc-Iturralde, Nevena Romanic-Bubalo, Ignacio Díaz-Aljaro, Zhongdi Chu, Ruikang K. Wang and Xavier Valldeperas
J. Clin. Med. 2024, 13(10), 2835; https://doi.org/10.3390/jcm13102835 - 11 May 2024
Viewed by 197
Abstract
Objective: To analyze the performance of custom semi-automated software for quantitative analysis of retinal capillaries in eyes with macula-off rhegmatogenous retinal detachment (RRD) and the role of these microvascular measures as potential biomarkers of postoperative visual outcomes. Methods: A prospective, observational, [...] Read more.
Objective: To analyze the performance of custom semi-automated software for quantitative analysis of retinal capillaries in eyes with macula-off rhegmatogenous retinal detachment (RRD) and the role of these microvascular measures as potential biomarkers of postoperative visual outcomes. Methods: A prospective, observational, and single-center study was conducted on consecutive patients who underwent 25G pars-plana vitrectomy for primary uncomplicated macula-off RRD. Optical coherence tomography angiography (OCTA) was performed in the fellow and RRD eyes before surgery and in months 1, 3, and 6 after surgery. The preoperative values of the fellow eyes were used as surrogates of macula-off ones. The primary endpoints were the mean vessel diameter index (VDI); vessel area density (VAD); and vessel skeleton density (VSD) at month 6. Results: Forty-four eyes (44 patients) were included in the study. Considering the fellow eyes as a surrogate of preoperative values of macula-off eyes, VDI in superficial (SCP) and deep (DCP) capillary plexuses was significantly reduced at month 6 (p = 0.0087 and p = 0.0402, respectively); whereas VSD in SCP increased significantly from preoperative values (p = 0.0278). OCTA built-in software parameters were significantly reduced from month 1 to month 6 in both SCP and DCP (p values ranged between 0.0235 and <0.0001). At month 6, 25 (56.8%) eyes achieved a best-corrected visual acuity BCVA ≥ 0.3 (LogMAR). The greater the preoperative BCVA, the greater the probability of achieving good visual outcomes (Odds ratio: 11.06; p = 0.0037). However, none of the OCTA parameters were associated with the probability of achieving a BCVA improvement ≥ 0.3. Conclusions: Quantitative evaluation of capillary density and morphology through OCTA and semi-automated software represents a valuable tool for clinical assessment and managing the disease comprehensively. Full article
(This article belongs to the Special Issue Advancements and Challenges in Retina Surgery)
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10 pages, 3789 KiB  
Article
Optimizing Surgical Management for Rhegmatogenous Retinal Detachment in Eyes with Active Retinoblastoma: A Safety-Driven Approach
by Yacoub A. Yousef, Omar AlHabahbeh, Mona Mohammad, Hadeel Halalsheh, Mustafa Mehyar, Mario Damiano Toro and Ibrahim AlNawaiseh
J. Clin. Med. 2024, 13(9), 2511; https://doi.org/10.3390/jcm13092511 - 25 Apr 2024
Viewed by 414
Abstract
Introduction: Intraocular surgeries are conventionally contraindicated for patients with active retinoblastoma (Rb) due to the potential risk of tumor dissemination. However, surgery is occasionally necessary to preserve vision in patients with a single eye when the eye is complicated by rhegmatogenous retinal detachment [...] Read more.
Introduction: Intraocular surgeries are conventionally contraindicated for patients with active retinoblastoma (Rb) due to the potential risk of tumor dissemination. However, surgery is occasionally necessary to preserve vision in patients with a single eye when the eye is complicated by rhegmatogenous retinal detachment (RRD). Objective: This study aims to evaluate the outcomes of surgical repair for RRD in pediatric patients with active Rb utilizing a non-drainage scleral buckling approach. Results: This cohort included six eyes from six patients who harbored active Rb and presented with RRD; one had a concurrent tractional component. All eyes (100%) had active intraocular Rb and were undergoing active therapy (systemic chemotherapy, cryotherapy, and thermal laser therapy) when RRD developed. RRD consistently manifested at the site of recent cryotherapy in all cases. RRD repair in the affected eyes was performed by scleral buckling without subretinal fluid drainage. Five of the six eyes (83%) achieved complete retinal reattachment. One eye (17%) with a tractional component exhibited partial reattachment and was eventually enucleated due to persistent active disease. At a median follow-up of 15 months (range 12–180 months) after scleral buckling, all five eyes had persistent retinal attachment, and no case developed orbital or distant metastasis. Conclusions: Our study demonstrates that nondrainage scleral buckling is an effective and safe method for the surgical repair of RRD in eyes harboring active Rb, as most cases achieved persistent complete retinal reattachment without the risk of tumor spread. Full article
(This article belongs to the Special Issue Advancements and Challenges in Retina Surgery)
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