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Clinical Application of Transcranial Magnetic Stimulation (TMS)
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Clinical Application of Transcranial Magnetic Stimulation (TMS)

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Clinical Neurology".

Deadline for manuscript submissions: 25 July 2024 | Viewed by 901

Special Issue Editor

Dr. Sebastian Ille

E-Mail Website
Guest Editor
Department of Neurosurgery, School of Medicine, Klinikum Rechts Der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany
Interests: transcranial magnetic stimulation (TMS); brain tumors; brain imaging; neuroimaging; brain stimulation; brain mapping; cognitive neuroscience; neuroplasticity

Special Issue Information

Dear Colleagues,

Transcranial magnetic stimulation (TMS) has evolved from a research tool to a highly standardized technique that can be used in daily clinical routines. Through its non-invasiveness and when combined with neuronavigation (nTMS), the technique per se offers multiple options regarding the diagnostics, therapy, or rehabilitation of patients suffering from various pathologies. Apart from my own focus on the pre-, intra-, and postoperative clinical application of nTMS in neurosurgery, several types of medical professionals, such as neurologists, psychiatrists, pediatricians, pain therapists, or rehabilitation physicians, also clinically apply TMS.

The purpose of this Special Issue is to give a comprehensive overview summarizing the latest research on the clinical application of TMS for 1) cortical brain mapping and monitoring of functionality, 2) its use as a basis for anatomical tractography or connectome analysis, 3) therapy of neurological and psychiatric diseases, pain and further pathologies, 4) support and therapy during neurorehabilitation, 5) the impact on the patients’ clinical, functional, or oncological outcome, 6) as well as the visualization of functional reorganization or therapy effects. This Special Issue welcomes both original research articles and reviews.

Dr. Sebastian Ille
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • transcranial magnetic stimulation
  • neuronavigation
  • brain mapping
  • TMS diagnostics
  • TMS therapy
  • neurorehabilitation

Published Papers (1 paper)

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Research

12 pages, 1766 KiB  
Article
Systematic Evaluation of the Effects of Voluntary Activation on Lower Extremity Motor Thresholds
by Jasmine J. Cash, Mark G. Bowden, Andrea D. Boan, Lisa M. McTeague and John H. Kindred
J. Clin. Med. 2023, 12(18), 5993; https://doi.org/10.3390/jcm12185993 - 15 Sep 2023
Viewed by 692
Abstract
The purpose of this investigation was to elucidate the relationship between the resting motor threshold (rMT) and active motor threshold (aMT). A cross-sectional comparison of MTs measured at four states of lower extremity muscle activation was conducted: resting, 5% maximal voluntary contraction (MVC), [...] Read more.
The purpose of this investigation was to elucidate the relationship between the resting motor threshold (rMT) and active motor threshold (aMT). A cross-sectional comparison of MTs measured at four states of lower extremity muscle activation was conducted: resting, 5% maximal voluntary contraction (MVC), 10%MVC, and standing. MTs were measured at the tibialis anterior in the ipsilesional and contralesional limbs in participants in the chronic phase (>6 months) of stroke (n = 11) and in the dominant limb of healthy controls (n = 11). To compare across activation levels, the responses were standardized using averaged peak-to-peak background electromyography (EMG) activity measured at 10%MVC + 2SD for each participant, in addition to the traditional 0.05 mV criterion for rMT (rMT50). In all participants, as muscle activation increased, the least square mean estimates of MTs decreased (contralesional: p = 0.008; ipsilesional: p = 0.0015, healthy dominant: p < 0.0001). In healthy controls, rMT50 was significantly different from all other MTs (p < 0.0344), while in stroke, there were no differences in either limb (p > 0.10). This investigation highlights the relationship between rMT and aMTs, which is important as many stroke survivors do not present with an rMT, necessitating the use of an aMT. Future works may consider the use of the standardized criterion that accounted for background EMG activity across activation levels. Full article
(This article belongs to the Special Issue Clinical Application of Transcranial Magnetic Stimulation (TMS))
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