Colon and Rectal Surgery: Current Clinical Practice and Future Trends

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "General Surgery".

Deadline for manuscript submissions: 25 August 2024 | Viewed by 832

Special Issue Editor


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Guest Editor
Second Department of Surgery, University General Hospital of Alexandroupolis, Democritus University of Thrace Medical School, 68100 Alexandroupolis, Greece
Interests: surgical oncology; colorectal cancer surgery; colorectal surgery; laparoscopic surgery; artificial intelligence in surgery; minimally invasive surgery; cellular metabolism in colorectal cancer; metastasis; gastrointestinal surgery; abdominal surgery
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Special Issue Information

Dear Colleagues,

At present, there are various trends, new challenges, and future directions regarding colorectal surgery. Colorectal cancer represents a leading cause of cancer-related deaths worldwide. Surgical treatment of colorectal cancer patients is mainly driven by the stage at presentation, highlighting the need for prompt diagnosis, evaluation, and management. Colon and rectal surgery is commonly associated with severe postoperative complications that may have a substantial impact on patient morbidity and mortality. Integrating enhanced recovery protocols in colon and rectal surgery has been revealed to reduce complication and mortality rates and improve postoperative survival and quality of life. In recent decades, surgical treatment has made significant progress. Nevertheless, the presence of metastasis, including lymph node involvement, affects patient survival and remains another challenging issue for both surgical treatment and accurate preoperative evaluation. With the intent of treating colorectal cancer patients and predicting their prognosis despite the progress in surgical approaches, intensive research on altered cancer metabolism will eventually lead to combined management strategies in the future. Novel techniques, including artificial intelligence models, have been used in order to achieve better outcomes during and after colorectal surgery. Such technological advances are steadily gaining ground in the field of surgery. This Special Issue aims to highlight current clinical practice and reveal future perspectives in colon and rectal surgery.

Dr. Konstantinos Romanidis
Guest Editor

Manuscript Submission Information

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Keywords

  • colorectal surgery
  • colorectal cancer
  • complications
  • metastasis
  • artificial intelligence
  • cancer metabolism

Published Papers (1 paper)

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Research

10 pages, 596 KiB  
Article
The Outcome of Local Excision of Rectal Adenomas with High-Grade Dysplasia by Transanal Endoscopic Microsurgery: A Single-Center Experience
by Muhammad Khalifa, Rachel Gingold-Belfer and Nidal Issa
J. Clin. Med. 2024, 13(5), 1419; https://doi.org/10.3390/jcm13051419 - 29 Feb 2024
Viewed by 652
Abstract
Background: Local excision by transanal endoscopic microsurgery (TEM) is considered an acceptable treatment for rectal adenomas with high-grade dysplasia (HGD). This study aims to assess the likelihood of harboring an invasive carcinoma in preoperatively diagnosed HGD polyps and evaluate the risk factors [...] Read more.
Background: Local excision by transanal endoscopic microsurgery (TEM) is considered an acceptable treatment for rectal adenomas with high-grade dysplasia (HGD). This study aims to assess the likelihood of harboring an invasive carcinoma in preoperatively diagnosed HGD polyps and evaluate the risk factors for tumor recurrence in patients with final HGD pathology. Methods: Data from patients who underwent TEM procedures for adenomatous lesions with HGD from 2005 to 2018 at the Rabin Medical Center, Hasharon Hospital, were analyzed. Collected data included patient demographics, preoperative workup, tumor characteristics and postoperative results. Follow-up data including recurrence assessment and further treatments were reviewed. The analysis included two subsets: preoperative pathology of HGD (sub-group 1) and postoperative final pathology of HGD (sub-group 2) patients. Results: Forty-five patients were included in the study. Thirty-six patients had a preoperative diagnosis of HGD, with thirteen (36%) showing postoperative invasive carcinoma. Thirty-two patients had a final pathology of HGD, and three (9.4%) experienced tumor recurrence. Large tumor size (>5 cm) was significantly associated with recurrence (p = 0.03). Conclusions: HGD rectal polyps are associated with a significant risk of invasive cancer. Tumor size was a significant factor in predicting tumor recurrence in patients with postoperative HGD pathology. The TEM procedure is an effective first-line treatment for such lesions. Full article
(This article belongs to the Special Issue Colon and Rectal Surgery: Current Clinical Practice and Future Trends)
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

1. title: The simultaneous use of APACHE II and NEWS II clinical scores in postoperative monitoring of the colon and rectum surgical patient
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