Personalized Therapy and Clinical Advances for Congenital Heart Disease

Dear Colleagues,

Congenital heart disease is the most common of all congenital defects, and patients with this disease have markedly benefited from advances in medicine and surgery over recent decades, with most of them reaching adulthood. Due to the peculiarities of patients with congenital heart disease, including hospital admissions, surgery, interventional procedures, device implantation, etc., it is of special interest to guide them in a targeted manner.

Personalized therapy provides medical care to treat patients and includes genetics, inheritance, biochemical and behavioral aspects, and lifestyle, providing information on morbimortality and determining the right treatment for the right patient at the right time. Also, artificial intelligence developments in the form of new and emerging technologies and the analysis of large data collections may identify factors that discriminate groups of individuals that might benefit from different interventions. Identifying the best approach to personalized medicine requires the ability to interpret detailed patient data together with broader aspects to track and differentiate between sick and relatively healthy individuals even among those with congenital heart disease.

As personalized medicine is a medical model that aims to provide tailor-made prevention and treatment strategies and considering the great heterogenicity seen among the different types of congenital heart diseases, it is of paramount importance to obtain tools that help us to focus on the right direction.

Dr. Efrén Martínez-Quintana
Guest Editor

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• congenital heart disease
• genetics
• inheritance
• biochemical
• behavioral
• lifestyle
• artificial intelligence